Gene: EXOC3L2
Official Full Name: exocyst complex component 3 like 2provided by HGNC
Gene Summary: The protein encoded by this gene is upregulated by vascular endothelial growth factor A and interacts with exocyst complex component 4. The encoded protein may be part of an exocyst complex that plays a role in cell membrane dynamics. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23774 | EXOC3L2 Knockout cell line (HeLa) | Human | EXOC3L2 | 1:3~1:6 | Negative | Online Inquiry |
KO23775 | EXOC3L2 Knockout cell line (HCT 116) | Human | EXOC3L2 | 1:2~1:4 | Negative | Online Inquiry |
KO23776 | EXOC3L2 Knockout cell line (A549) | Human | EXOC3L2 | 1:3~1:4 | Negative | Online Inquiry |
EXOC3L2 Gene Knockout Cell Lines are specifically engineered cellular models that enable detailed exploration of the EXOC3L2 gene's role in various biological processes. By employing CRISPR-Cas9 gene-editing technology, these knockout cell lines have effectively silenced the expression of the EXOC3L2 gene, providing researchers with a powerful tool to investigate its functional consequences in cellular pathways, including those involved in exocytosis and cellular signaling.
The primary mechanism underlying the functionality of the EXOC3L2 knockout cell lines lies in their ability to mimic gene loss-of-function scenarios. By studying these cells, researchers can elucidate the effects of EXOC3L2 ablation on cellular physiology, protein interactions, and molecular pathways. Investigations using these cell lines can significantly advance our understanding of diseases where EXOC3L2 is implicated, such as certain neurological disorders or conditions linked to secretory pathway dysfunction.
The scientific importance of EXOC3L2 Gene Knockout Cell Lines extends to both basic research and therapeutic application. In basic research, they serve as invaluable models for screening drugs targeting associated pathways and for the development of gene therapies. In clinical settings, these cell lines can help identify novel biomarkers and inform personalized medicine approaches by elucidating patient-specific gene interactions and responses.
Distinct from conventional cell models, the unique selling points of the EXOC3L2 Gene Knockout Cell Lines include their precise genetic modification, which allows for rigorous validation of experimental outcomes, as well as the critical insights they can provide into the broader regulatory networks of cellular functions. Unlike other gene intervention strategies that may exhibit off-target effects, the CRISPR-Cas9 technology employed ensures high specificity and efficiency in gene knockout.
Researchers and clinicians will find value in utilizing these knockout cell lines, as they facilitate the generation of reproducible data essential for advancing scientific knowledge and biomedical research. Their applications not only promise novel discovery avenues but can also contribute meaningfully to the development of innovative therapies.
With extensive expertise in genetic modeling and a commitment to high-quality biological products, our company is dedicated to providing researchers with premier resources that enhance the scope and impact of their scientific investigations.
Please note that all services are for research use only. Not intended for any clinical use.
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