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ERLEC1 Knockout Cell Lines

Gene: ERLEC1

Official Full Name: endoplasmic reticulum lectin 1provided by HGNC

Gene Summary: This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27695 ERLEC1 Knockout cell line (HeLa) Human ERLEC1 1:3~1:6 Negative Online Inquiry
KO27696 ERLEC1 Knockout cell line (HCT 116) Human ERLEC1 1:2~1:4 Negative Online Inquiry
KO27697 ERLEC1 Knockout cell line (HEK293) Human ERLEC1 1:3~1:6 Negative Online Inquiry
KO27698 ERLEC1 Knockout cell line (A549) Human ERLEC1 1:3~1:4 Negative Online Inquiry

Background

ERLEC1 Gene Knockout Cell Lines are engineered cellular models that harbor targeted deletions of the ERLEC1 gene, providing a powerful tool for researchers in the fields of genetics, cell biology, and molecular medicine. These knockout lines facilitate the study of ERLEC1's roles in various physiological processes and disease states, particularly in relation to cellular responses to stress and inflammatory signaling pathways.

The primary function of these cell lines is to enable the elucidation of ERLEC1's contributions to cell signaling and metabolism. By completely knocking out the gene, researchers can assess changes in cellular behavior, gene expression, and protein interactions that may arise from the absence of ERLEC1, allowing for a comprehensive understanding of its biological significance. This mechanistic insight can drive discoveries in areas such as cancer research, neurodegenerative diseases, and metabolic disorders.

In both research and clinical settings, ERLEC1 Gene Knockout Cell Lines hold substantial scientific value, offering a platform for drug discovery, biomarker identification, and the development of targeted therapies. The ability to draw mechanistic correlations between ERLEC1 function and various disease pathways provides a competitive edge in uncovering new therapeutic targets.

Compared to traditional knockout models, our ERLEC1 Gene Knockout Cell Lines offer enhanced specificity and robustness, giving researchers confidence in their experimental outcomes. They are pre-validated for consistent performance across experiments, which streamlines workflow and increases the reproducibility of results.

We understand the challenges faced by researchers and clinicians in their quest for reliable biological tools. Our expertise in cell line engineering ensures that the ERLEC1 Gene Knockout Cell Lines are not only scientifically sound but also tailored to meet the needs of modern research environments. Choosing our product means investing in cutting-edge technology that accelerates discovery and innovation in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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