Gene: EPB41L3
Official Full Name: erythrocyte membrane protein band 4.1 like 3provided by HGNC
Gene Summary: Predicted to enable cytoskeletal protein-membrane anchor activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including nervous system development; paranodal junction maintenance; and protein localization to axon. Located in cell-cell junction and plasma membrane. Implicated in esophagus squamous cell carcinoma. Biomarker of meningioma. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01745 | EPB41L3 Knockout cell line (HEK293) | Human | EPB41L3 | 1:3~1:6 | Negative | Online Inquiry |
KO01746 | EPB41L3 Knockout cell line (A549) | Human | EPB41L3 | 1:3~1:4 | Negative | Online Inquiry |
EPB41L3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the functional EPB41L3 gene, which encodes a member of the erythrocyte membrane protein band 4.1 family. This gene plays a crucial role in maintaining cell membrane integrity and cytoskeletal structure. The knockout of EPB41L3 allows researchers to study the gene's function by observing the resulting phenotypic changes, thereby providing insights into various cellular processes including cell adhesion, migration, and signal transduction.
These engineered cell lines facilitate a deeper understanding of the pathological conditions linked to EPB41L3 dysregulation, including cancer, cardiovascular diseases, and neurological disorders. By employing techniques such as CRISPR/Cas9 gene editing, EPB41L3 Knockout Cell Lines demonstrate precise genetic modification, which is paramount for functional assays in drug discovery and therapeutic development. The absence of EPB41L3 serves as a powerful tool to dissect the molecular pathways regulated by this gene, ultimately aiding in identifying potential therapeutic targets.
What sets the EPB41L3 Gene Knockout Cell Lines apart from conventional models is their specificity and the reproducibility of results they yield. Traditional cell lines may exhibit variability and lack the control necessary for precise experimental outcomes; however, the knockout strategy ensures consistent expression profiles, enhancing the reliability of research findings.
For researchers and clinicians, these cell lines offer a significant advantage both in speed and cost-effectiveness, enabling swift exploration of genetic influences on disease progression and treatment efficacy. They are indispensable for laboratories focused on translational research, allowing scientists to rapidly iterate through experimental designs with confidence.
At our company, we specialize in providing advanced genetic tools and engineered cellular models, underpinned by a commitment to innovation and scientific accuracy. Our EPB41L3 Gene Knockout Cell Lines exemplify this dedication, equipping researchers with the necessary resources to elucidate complex biological phenomena and drive meaningful advancements in health science.
Please note that all services are for research use only. Not intended for any clinical use.
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