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ENTPD4 Knockout Cell Lines

Gene: ENTPD4

Official Full Name: ectonucleoside triphosphate diphosphohydrolase 4provided by HGNC

Gene Summary: This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33071 ENTPD4 Knockout cell line (HeLa) Human ENTPD4 1:3~1:6 Negative Online Inquiry
KO33072 ENTPD4 Knockout cell line (HCT 116) Human ENTPD4 1:2~1:4 Negative Online Inquiry
KO33073 ENTPD4 Knockout cell line (HEK293) Human ENTPD4 1:3~1:6 Negative Online Inquiry
KO33074 ENTPD4 Knockout cell line (A549) Human ENTPD4 1:3~1:4 Negative Online Inquiry

Background

ENTPD4 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology research, specifically engineered to disable the ENTPD4 gene, which encodes ecto-nucleotide triphosphate diphosphohydrolase 4. This enzyme plays a crucial role in regulating extracellular nucleotide levels, thereby influencing various physiological processes, including immune response and tumorigenesis. By utilizing CRISPR/Cas9 technology, these cell lines allow researchers to study the functional consequences of ENTPD4 loss, providing insights into its role in health and disease.

The primary function of ENTPD4 involves the hydrolysis of nucleotides, converting nucleoside triphosphates into diphosphates. This biochemical activity impacts purinergic signaling pathways and cellular communication. By utilizing these knockout cell lines, scientists can explore the downstream effects of ENTPD4 deletion, thereby elucidating its involvement in regulatory mechanisms related to cell proliferation, apoptosis, and immune modulation. Understanding these pathways is fundamental in both therapeutic developments and basic biological research.

The scientific importance of ENTPD4 knockout cell lines lies in their versatility for various applications, from basic biological studies to translational research in oncology and immunology. Investigating these lines can lead to the discovery of innovative therapeutic targets, enriching our understanding of disease mechanisms and fostering the development of novel treatments or interventions.

What sets our ENTPD4 Gene Knockout Cell Lines apart from alternatives is their precise genetic modification, ensuring high specificity and reproducibility in experiments. Furthermore, our product includes comprehensive documentation and supportive data demonstrating functionality, enabling researchers to make informed decisions and achieve actionable results more efficiently.

For researchers, clinicians, and other stakeholders in the biomedical field, the value of ENTPD4 Gene Knockout Cell Lines lies in their potential to advance knowledge and facilitate breakthroughs. As a leader in cellular research tools, our company is committed to providing high-quality biological products backed by strong scientific expertise and comprehensive support, empowering the next generation of discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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