Gene: ELF3
Official Full Name: E74 like ETS transcription factor 3provided by HGNC
Gene Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in inflammatory response; negative regulation of DNA-templated transcription; and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00156 | ELF3 Knockout cell line (HEK293) | Human | ELF3 | 1:3~1:6 | Negative | Online Inquiry |
KO00194 | ELF3 Knockout cell line (HeLa) | Human | ELF3 | 1:3~1:6 | Negative | Online Inquiry |
KO00195 | ELF3 Knockout cell line (A549) | Human | ELF3 | 1:3~1:4 | Negative | Online Inquiry |
KO06463 | ELF3 Knockout cell line (HCT 116) | Human | ELF3 | 1:2~1:4 | Negative | Online Inquiry |
ELF3 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the ELF3 (E74-like factor 3) gene, a critical transcription factor involved in various cellular processes including growth, differentiation, and immune regulation. This product provides a powerful platform for researchers to study the biological implications of ELF3 deficiency in multiple contexts, particularly its roles in cancer biology and immune response mechanisms.
The key function of ELF3 Gene Knockout Cell Lines lies in their ability to elucidate the downstream regulatory pathways influenced by ELF3. By employing CRISPR-Cas9 technology, these cell lines enable precise disruption of the ELF3 gene, facilitating studies on how its absence alters cellular behaviors such as proliferation, migration, and apoptosis. Through functional assays, scientists can analyze gene expression changes and assess phenotypic variations that emerge from ELF3 knockout, providing insights into its role in oncogenesis and potential pathways for therapeutic intervention.
In the realm of scientific research, ELF3 Gene Knockout Cell Lines are invaluable for their applications in oncological studies, immunological assays, and drug discovery. These models allow for high-throughput screening of compounds that may modify the effects of ELF3 deletion, offering pathways for novel therapeutic strategies targeting ELF3-related pathways. Their use in exploratory studies can lead to significant advancements in understanding diseases characterized by dysregulated ELF3 activity, paving the way for innovative treatment options.
Compared to alternative cell lines, ELF3 Gene Knockout Cell Lines provide unique advantages including specificity of gene targeting, reproducibility of results, and versatility across different experimental setups. This specificity allows researchers to discern the direct impacts of ELF3 loss without confounding effects from other genetic variations, making these cell lines superior for targeted experimentation.
For researchers and clinicians seeking to uncover the complexities of gene function in cellular processes, ELF3 Gene Knockout Cell Lines offer a robust tool that enhances experimental precision and depth of analysis. Our company specializes in developing cutting-edge genetic models, backed by rigorous validation processes, ensuring that our products meet the highest standards of quality and reliability for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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