Gene: EID2
Official Full Name: EP300 interacting inhibitor of differentiation 2provided by HGNC
Gene Summary: Enables SMAD binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transforming growth factor beta receptor complex assembly. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18049 | EID2 Knockout cell line (HeLa) | Human | EID2 | 1:3~1:6 | Negative | Online Inquiry |
KO18050 | EID2 Knockout cell line (HCT 116) | Human | EID2 | 1:2~1:4 | Negative | Online Inquiry |
KO18051 | EID2 Knockout cell line (HEK293) | Human | EID2 | 1:3~1:6 | Negative | Online Inquiry |
KO18052 | EID2 Knockout cell line (A549) | Human | EID2 | 1:3~1:4 | Negative | Online Inquiry |
EID2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the EID2 gene, a critical regulator involved in various biological pathways, including cell proliferation, differentiation, and apoptosis. By utilizing CRISPR-Cas9 technology, these cell lines facilitate precise genomic editing, enabling researchers to explore the functional implications of EID2 depletion in a controlled environment. The knockout of EID2 results in altered cellular behaviors, making these cell lines indispensable for investigating the gene's role in disease mechanisms, particularly in cancer and metabolic disorders.
The primary function of EID2 is its involvement in chromatin remodeling, which influences transcriptional regulation. This alteration in gene expression profiles can help delineate the pathways that EID2 interacts with, providing valuable insights into cellular processes like signal transduction and stress response. The unique ability of these knockout cell lines to illuminate the downstream effects of EID2 disruption empowers researchers to model pathological conditions and identify potential therapeutic targets.
In both research and clinical settings, the EID2 Gene Knockout Cell Lines hold significant scientific importance. They serve as effective tools for drug screening, biomarker discovery, and experimental validation of gene function. Their capacity to reproduce phenotypic changes associated with EID2 loss enhances their utility in translational research, bridging the gap between laboratory findings and clinical applications.
One of the key advantages of using EID2 Gene Knockout Cell Lines over alternative methods is the specificity and efficiency of the CRISPR-Cas9 system, which allows for the targeted disruption of the EID2 gene without affecting neighboring genes. This specificity minimizes off-target effects, providing researchers with more reliable data. Additionally, the standardization and reproducibility of these cell lines make them an attractive choice for collaborative projects and multi-laboratory studies.
For researchers and clinicians alike, the EID2 Gene Knockout Cell Lines offer a robust platform for advancing understanding in molecular biology and genetics. Their ability to elucidate gene function in important biological processes is invaluable for developing innovative therapeutic strategies. Our company, with its extensive expertise in genetic engineering and cell line development, is committed to delivering high-quality biological products to facilitate groundbreaking research and foster scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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