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EFHD1 Knockout Cell Lines

Gene: EFHD1

Official Full Name: EF-hand domain family member D1provided by HGNC

Gene Summary: This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26051 EFHD1 Knockout cell line (HeLa) Human EFHD1 1:3~1:6 Negative Online Inquiry
KO26052 EFHD1 Knockout cell line (HEK293) Human EFHD1 1:3~1:6 Negative Online Inquiry
KO26053 EFHD1 Knockout cell line (A549) Human EFHD1 1:3~1:4 Negative Online Inquiry

Background

EFHD1 Gene Knockout Cell Lines represent a groundbreaking innovation in the field of genetic research and cellular biology. These specialized cell lines have undergone targeted gene disruption to inactivate the EFHD1 gene, which encodes the EF-hand domain-containing protein 1, a protein implicated in various cellular processes, including signal transduction, calcium homeostasis, and cellular response to stress. By utilizing CRISPR-Cas9 technology, these knockout cell lines are engineered to provide researchers with a robust tool for studying the phenotypic consequences of EFHD1 deficiency.

The primary function of EFHD1 Gene Knockout Cell Lines lies in their ability to facilitate in-depth investigations into the role of EFHD1 in cellular mechanisms and pathways. By comparing these knockout lines to their wild-type counterparts, researchers can elucidate the gene's involvement in processes such as apoptosis, cellular proliferation, and differentiation. Additionally, these cell lines can serve as valuable models for understanding disease mechanisms, particularly in neurology and cancer biology, where EFHD1 has been linked to critical pathophysiological processes.

Importantly, these knockout cell lines offer significant advantages over traditional methods such as RNA interference. The complete and stable gene disruption ensures that researchers can achieve reproducible results, allowing for more reliable data on gene function. The versatility of EFHD1 Gene Knockout Cell Lines makes them suitable for various applications, including drug development, functional genomics, and basic research studies.

Researchers and clinicians looking to explore the intricacies of EFHD1's biological roles will find these cell lines invaluable. Their specificity and reliability empower users to gain insights into cellular dynamics that can drive therapeutic advancements.

With expertise rooted in cutting-edge genetic engineering and a commitment to advancing biological research, our company stands at the forefront of providing high-quality research tools such as EFHD1 Gene Knockout Cell Lines, enabling scientists to unlock the complexities of cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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