Gene: EAF1
Official Full Name: ELL associated factor 1provided by HGNC
Gene Summary: Enables transcription elongation factor activity. Involved in regulation of transcription elongation by RNA polymerase II. Located in intercellular bridge and nuclear body. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24250 | EAF1 Knockout cell line (HeLa) | Human | EAF1 | 1:3~1:6 | Negative | Online Inquiry |
KO24251 | EAF1 Knockout cell line (HCT 116) | Human | EAF1 | 1:2~1:4 | Negative | Online Inquiry |
KO24252 | EAF1 Knockout cell line (HEK293) | Human | EAF1 | 1:3~1:6 | Negative | Online Inquiry |
KO24253 | EAF1 Knockout cell line (A549) | Human | EAF1 | 1:3~1:4 | Negative | Online Inquiry |
EAF1 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the EAF1 gene's role in cellular functions and disease mechanisms. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously developed to produce EAF1 gene disruptions, allowing researchers to investigate the consequences of gene loss on various biological pathways.
The key functionality of EAF1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for observing the effects of EAF1 protein absence. This includes elucidating its involvement in processes such as mRNA splicing and transcription regulation, both of which are critical for understanding gene expression profiles in diverse cellular contexts. By leveraging these knockout models, scientists can quantitatively assess downstream effects on cellular proliferation, apoptosis, and metabolic changes, thereby uncovering novel insights into the pathogenesis of diseases, including cancer.
In terms of scientific importance, these cell lines facilitate a thorough investigation of gene function and contribute significantly to drug discovery and developmental biology research. Their applications extend to pharmacogenomics, where they can be used to identify potential therapeutic targets, as well as systems biology to model complex cellular interactions.
Compared to traditional cellular models, EAF1 Gene Knockout Cell Lines offer enhanced specificity and reliability in studying gene function with lower background noise. They are designed for ease of use and rapid integration into existing research workflows, thus saving time and resources.
For researchers and clinicians seeking to unravel the complexities of genetic influences on health and disease, these cell lines are invaluable tools. They empower detailed mechanistic studies that can drive innovation in therapeutic techniques and lead to breakthroughs in understanding genetic contributions to pathology.
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Please note that all services are for research use only. Not intended for any clinical use.
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