Gene: DZIP1
Official Full Name: DAZ interacting zinc finger protein 1provided by HGNC
Gene Summary: Enables BBSome binding activity and molecular adaptor activity. Involved in cilium organization; heart development; and protein-containing complex localization to centriolar satellite. Located in cytoplasm; microtubule organizing center; and nucleoplasm. Implicated in mitral valve prolapse and spermatogenic failure 47. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30231 | DZIP1 Knockout cell line (HeLa) | Human | DZIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO30232 | DZIP1 Knockout cell line (HEK293) | Human | DZIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO30233 | DZIP1 Knockout cell line (A549) | Human | DZIP1 | 1:3~1:4 | Negative | Online Inquiry |
DZIP1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the exploration of the DZIP1 gene's role in cellular processes and disease states. The DZIP1 gene is implicated in the regulation of several biological pathways, notably in the modulation of signaling cascades that influence neuronal development and function. By creating knockout cell lines where the DZIP1 gene is disrupted, researchers are equipped to investigate its functions and contributions to various physiological and pathological conditions, providing an indispensable tool for genetic and pharmaceutical studies.
The primary mechanism of action for these knockout cell lines hinges on the targeted deletion of the DZIP1 gene, achieved through advanced gene-editing techniques such as CRISPR/Cas9 or other homologous recombination methods. This targeted approach enables a clear assessment of DZIP1's influence on cellular phenotypes, including its impact on neurogenesis, apoptosis, and synaptic integrity. Furthermore, these cell lines are critical for high-throughput screening of therapeutic compounds aimed at related conditions, including neurodevelopmental disorders and neurodegenerative diseases.
From a scientific perspective, DZIP1 Gene Knockout Cell Lines hold significant implications in both research and clinical contexts. Researchers can utilize these models to deepen their understanding of gene function and interactions in complex biological systems, paving the way for novel therapeutic strategies. Moreover, data generated from studies utilizing these cell lines can provide valuable insights that lead to the development of biomarker-driven approaches and targeted therapies.
What sets our DZIP1 Gene Knockout Cell Lines apart from other genetic models is our commitment to precise gene editing and quality assurance. Each cell line is validated through comprehensive genetic and phenotypic characterization to ensure accurate representation of the gene knockout. This guarantees researchers that their experiments are based on robust and reliable cellular systems.
In conclusion, DZIP1 Gene Knockout Cell Lines are indispensable for researchers seeking to explore genetic functions and therapeutic interventions. With our extensive expertise in gene editing technologies and dedication to providing high-quality biological products, we empower scientists and clinicians to challenge the boundaries of current biomedical research and foster advancements in healthcare.
Please note that all services are for research use only. Not intended for any clinical use.
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