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DRG2 Knockout Cell Lines

Gene: DRG2

Official Full Name: developmentally regulated GTP binding protein 2provided by HGNC

Gene Summary: This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38175 DRG2 Knockout cell line (HeLa) Human DRG2 1:3~1:6 Negative Online Inquiry
KO38176 DRG2 Knockout cell line (HCT 116) Human DRG2 1:2~1:4 Negative Online Inquiry
KO38177 DRG2 Knockout cell line (HEK293) Human DRG2 1:3~1:6 Negative Online Inquiry
KO38178 DRG2 Knockout cell line (A549) Human DRG2 1:3~1:4 Negative Online Inquiry

Background

DRG2 Gene Knockout Cell Lines are genetically engineered cells that have had the DRG2 gene specifically targeted and inactivated using CRISPR-Cas9 technology. This precise genetic modification allows researchers to investigate the biological functions of DRG2 in various cellular contexts. These cell lines serve as vital tools for studying gene function, protein interactions, and the molecular pathways related to critical biological processes.

The primary mechanism by which these knockout cell lines operate involves the disruption of the DRG2 gene coding sequence, ultimately leading to the absence of its corresponding protein product. The absence of DRG2 provides insights into its roles in cellular processes such as cell proliferation, apoptosis, and differentiation. This information can be instrumental for researchers examining the gene’s involvement in disease states, including neurodegeneration and cancer.

The scientific importance of DRG2 Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, they can facilitate drug discovery by serving as screening platforms to evaluate the effects of therapeutic compounds on cells missing DRG2. Furthermore, these cell lines enable the exploration of compensatory mechanisms that may arise in the absence of the gene, thereby offering a more comprehensive understanding of disease pathology.

Compared to traditional gene knockout methods, such as homologous recombination, the CRISPR-Cas9 technology used for generating DRG2 knockout cell lines results in quicker generation times and higher efficiency. Additionally, these cell lines are validated for consistent performance, ensuring reliable experimental outcomes.

For researchers and clinicians, these cell lines represent a unique and valuable resource for dissecting the roles of DRG2 in health and disease. By providing an efficient and effective way to study gene function, DRG2 Gene Knockout Cell Lines stand out as indispensable tools in the modern biological research toolkit.

Our company is dedicated to advancing research capabilities by providing high-quality, rigorously validated biological products. With expertise in genetic engineering and cellular biology, we offer a comprehensive portfolio of cell lines and related products to support scientific breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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