Gene: DLX1
Official Full Name: distal-less homeobox 1provided by HGNC
Gene Summary: This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01416 | DLX1 Knockout cell line(PC-3) | Human | DLX1 | 1:3~1:4 | Negative | Online Inquiry |
KO18271 | DLX1 Knockout cell line (HeLa) | Human | DLX1 | 1:3~1:6 | Negative | Online Inquiry |
KO18272 | DLX1 Knockout cell line (HCT 116) | Human | DLX1 | 1:2~1:4 | Negative | Online Inquiry |
KO18273 | DLX1 Knockout cell line (HEK293) | Human | DLX1 | 1:3~1:6 | Negative | Online Inquiry |
KO18274 | DLX1 Knockout cell line (A549) | Human | DLX1 | 1:3~1:4 | Negative | Online Inquiry |
DLX1 Gene Knockout Cell Lines are genetically engineered cellular systems designed specifically to facilitate the exploration of the role of the DLX1 gene in various biological processes. By employing the CRISPR-Cas9 gene-editing technology, these cell lines exhibit a targeted disruption of the DLX1 gene, allowing researchers to study the consequences of its absence on cellular function, differentiation, and behavior.
The key function of these knockout cell lines is to serve as a dynamic model to investigate the specific contributions of DLX1 to neurodevelopment, as it plays a pivotal role in neural patterning and the formation of complex behaviors. The precise knockout of the gene enables in-depth analysis of associated pathways, providing insights into underlying mechanisms in both healthy and diseased states. This functional dissection is crucial, especially in understanding disorders linked to neurodevelopmental aberrations, such as autism or schizophrenia.
Scientifically, the DLX1 Gene Knockout Cell Lines are invaluable in both basic research and translational medicine. They can be employed to elucidate gene function and interaction networks, accelerate drug discovery processes, and identify potential therapeutic targets within relevant signaling pathways. The specificity and reliability of these cell lines make them preferable for studies requiring reproducible results in cellular responses.
What sets these cell lines apart from alternatives is their robust genetic validation, high efficiency of knockout, and ease of use in various experimental setups. Researchers can expect excellent viability and performance during routine cell culture, ensuring consistent data quality.
For researchers and clinicians alike, the DLX1 Gene Knockout Cell Lines represent a critical tool in the genetic toolbox, bridging the gap between genetic research and clinical applications, ultimately contributing to advancements in understanding complex biological systems. Leveraging our extensive expertise in genomic technologies, our company is dedicated to providing top-tier biological products that empower scientific breakthroughs and enhance experimental capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
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