DLG2 Knockout Cell Lines

DLG2 Gene Knockout Cell Lines are genetically engineered cell lines that have had the DLG2 gene, critical for synaptic function and organization, selectively disrupted. DLG2, also known as SAP97, plays an integral role in anchoring neurotransmitter receptors and cell signaling pathways, thus influencing synaptic plasticity. The knockout of this gene allows researchers to investigate the consequences of DLG2 absence on neuronal behavior, signaling cascades, and overall cell health, enabling a better understanding of synaptic dysfunctions associated with various neurological disorders.

The primary function of DLG2 Gene Knockout Cell Lines is to serve as a model for studying the impact of disrupted DLG2 activity. Utilizing CRISPR-Cas9 technology, these knockout cell lines exhibit a complete absence of DLG2 protein, allowing researchers to perform functional assays, elucidate molecular pathways, and assess the effects on cell morphology and growth. This biomechanical manipulation accelerates the discovery of therapeutic targets and provides insights into the molecular basis of diseases such as schizophrenia, autism spectrum disorders, and Alzheimer’s disease.

The scientific importance of DLG2 Gene Knockout Cell Lines lies in their application across both basic research and clinical settings. By utilizing these models, investigators can dissect the underlying mechanisms of synaptic pathology and drug response, paving the way for novel pharmacological interventions and personalized medicine approaches. In clinical contexts, understanding the role of DLG2 in synaptic integrity could lead to breakthroughs in developing strategies for treating related cognitive impairments.

What sets our DLG2 Gene Knockout Cell Lines apart from alternatives on the market is the precision in gene editing and the comprehensive validation of our cell lines. Each cell line is thoroughly characterized for gene knockout efficiency and maintained under conditions that closely replicate in vivo environments. Our commitment to quality ensures that researchers receive reliable and reproducible models that enhance their experimental outcomes.

Dedicated to advancing scientific research, our company brings years of expertise in molecular biology and genetic engineering, providing researchers and clinicians with cutting-edge tools designed to facilitate innovative discoveries. With a robust support network and ongoing commitment to product improvement, we strive to be the partner of choice for those pushing the boundaries of biomedical science.