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DHRS7B Knockout Cell Lines

Gene: DHRS7B

Official Full Name: dehydrogenase/reductase 7Bprovided by HGNC

Gene Summary: Predicted to enable acylglycerone-phosphate reductase (NADP+) activity. Predicted to be involved in ether lipid biosynthetic process. Predicted to act upstream of or within several processes, including brown fat cell differentiation; phosphatidylcholine biosynthetic process; and regulation of cold-induced thermogenesis. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28539 DHRS7B Knockout cell line (HeLa) Human DHRS7B 1:3~1:6 Negative Online Inquiry
KO28540 DHRS7B Knockout cell line (HCT 116) Human DHRS7B 1:2~1:4 Negative Online Inquiry
KO28541 DHRS7B Knockout cell line (HEK293) Human DHRS7B 1:3~1:6 Negative Online Inquiry
KO28542 DHRS7B Knockout cell line (A549) Human DHRS7B 1:3~1:4 Negative Online Inquiry

Background

DHRS7B Gene Knockout Cell Lines are specialized cellular models engineered to specifically disrupt the DHRS7B gene, which encodes a member of the short-chain dehydrogenase/reductase (SDR) superfamily. This gene is implicated in various metabolic processes, including the metabolism of retinoids and alcohols, making it crucial for understanding cellular responses related to these pathways. The DHRS7B knockout technique leverages CRISPR-Cas9 neurogenetics, offering researchers a powerful tool to examine the gene's role in differentiating cellular behaviors, metabolism, and disease modeling.

The primary function of the DHRS7B knockout cell lines lies in their ability to facilitate the study of gene function and interaction in a controlled environment. By observing the phenotypic and biochemical alterations that arise from the absence of DHRS7B, researchers can gain insight into metabolic disorders and potential therapeutic interventions. These knockout models are invaluable for elucidating the pathways that DHRS7B influences, thus contributing to the understanding of related pathologies.

In addition to their scientific importance in basic research, DHRS7B Gene Knockout Cell Lines have significant applications in drug discovery and development. They provide a platform for screening potential therapeutic agents targeting metabolic disorders linked to the DHRS7B pathway. Compared to alternatives, such as overexpression systems or wild-type cell lines, these knockout models allow for a more physiologically relevant assessment of drug efficacy and toxicity.

Researchers and clinicians will find value in utilizing DHRS7B Gene Knockout Cell Lines due to their specificity, reproducibility, and the relevance of findings to human health. The ability to model genetic deficiencies accurately positions this product as an essential resource in metabolic research, offering unique insights that drive innovation in therapeutic development.

Our company prides itself on delivering state-of-the-art biological products backed by extensive expertise in genetic engineering and cellular biology. We are committed to supporting the research community with high-quality tools that advance scientific discovery and pave the way for novel treatments.

Please note that all services are for research use only. Not intended for any clinical use.

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