Gene: DHRS7
Official Full Name: dehydrogenase/reductase 7provided by HGNC
Gene Summary: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. [provided by RefSeq, Apr 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22344 | DHRS7 Knockout cell line (HeLa) | Human | DHRS7 | 1:3~1:6 | Negative | Online Inquiry |
KO22345 | DHRS7 Knockout cell line (HCT 116) | Human | DHRS7 | 1:2~1:4 | Negative | Online Inquiry |
KO22346 | DHRS7 Knockout cell line (HEK293) | Human | DHRS7 | 1:3~1:6 | Negative | Online Inquiry |
KO22347 | DHRS7 Knockout cell line (A549) | Human | DHRS7 | 1:3~1:4 | Negative | Online Inquiry |
DHRS7 Gene Knockout Cell Lines are genetically modified cell lines that specifically lack the DHRS7 gene, which encodes for a member of the short-chain dehydrogenase/reductase (SDR) family involved in various metabolic pathways. These knockout cell lines are invaluable tools for researchers seeking to elucidate the biological functions of the DHRS7 protein, as well as its role in lipid metabolism, steroidogenesis, and cellular response to oxidative stress.
The primary function of these cell lines stems from the absence of DHRS7, allowing scientists to investigate the specific contributions of this gene to various cellular processes. The mechanism behind the gene knockout involves precise CRISPR/Cas9 technology, which enables accurate targeting and disruption of the DHRS7 gene. Researchers can utilize these cell lines to study metabolic dysregulations, screen for potential drug targets, and explore the implications of DHRS7 deficiency in disease models.
The scientific significance of DHRS7 Gene Knockout Cell Lines is apparent in fields such as cancer research, endocrinology, and metabolic disorders. Their application extends to identifying biomarkers for diseases, testing therapeutic interventions, and understanding the molecular underpinnings of disorders linked to abnormal lipid metabolism.
Compared to traditional cell lines, these knockout models offer specificity and precision that enhance experimental robustness. The ability to study the gene in a controlled manner provides clarity in interpreting experimental data, thus saving time and resources. Moreover, while generic cell lines may produce ambiguous results due to background gene expression, the DHRS7-deficient models allow for clearer conclusions regarding the effects attributed directly to the gene of interest.
For researchers and clinicians, the value of utilizing DHRS7 Gene Knockout Cell Lines lies in their potential to drive innovation in therapeutic discovery and deepen our understanding of complex biological systems. Leveraging our advanced genetic engineering capabilities, our company specializes in providing high-quality, rigorously validated biological products tailored to meet the needs of the scientific community. Choose our knockout cell lines to gain cutting-edge insights into your research and contribute to the advancement of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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