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DENND5B Knockout Cell Lines

Gene: DENND5B

Official Full Name: DENN domain containing 5Bprovided by HGNC

Gene Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of triglyceride transport. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18320 DENND5B Knockout cell line (HeLa) Human DENND5B 1:3~1:6 Negative Online Inquiry
KO18321 DENND5B Knockout cell line (HCT 116) Human DENND5B 1:2~1:4 Negative Online Inquiry
KO18322 DENND5B Knockout cell line (HEK293) Human DENND5B 1:3~1:6 Negative Online Inquiry
KO18323 DENND5B Knockout cell line (A549) Human DENND5B 1:3~1:4 Negative Online Inquiry

Background

DENND5B Gene Knockout Cell Lines represent a revolutionary tool in molecular and cellular biology, specifically designed to elucidate the role of the DENND5B gene in various biological processes. Constructed using advanced CRISPR-Cas9 gene-editing technology, these cell lines allow for the deletion of the DENND5B gene, enabling researchers to investigate its functions and interactions in a cellular context.

The primary function of DENND5B Gene Knockout Cell Lines is to facilitate the study of gene pathways and regulatory mechanisms associated with DENND5B. By creating a knockout model, researchers can observe phenotypic changes, signaling pathways, and the gene’s role in specific cellular events, such as vesicle trafficking and cellular differentiation. This knockout model provides a powerful means for researchers to draw conclusions about the biological implications of DENND5B, contributing to a nuanced understanding of gene function.

From a scientific perspective, the DENND5B gene has been highlighted for its potential involvement in various disorders, including neurological and metabolic conditions. Thus, these knockout cell lines are invaluable in both fundamental research and translational studies, providing insights that may lead to novel therapeutic strategies.

Compared to alternative genetic manipulation strategies, such as siRNA or traditional gene knockout techniques, our DENND5B Gene Knockout Cell Lines offer unrivaled specificity and efficiency. The CRISPR-Cas9 system ensures precise gene disruption without the complications of off-target effects, allowing for robust experimental results. Furthermore, these cell lines are readily available and can be easily integrated into existing research protocols, significantly streamlining experimental workflows.

By offering DENND5B Gene Knockout Cell Lines, we aim to empower researchers and clinicians to advance their studies with confidence. The ability to dissect the role of DENND5B in various biological contexts opens doors to hypotheses that could ultimately drive innovative therapeutic developments. As a company committed to supporting scientific discovery, we leverage our expertise in gene editing and cellular biology to provide high-quality biological products that meet the rigorous standards of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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