Gene: DECR2
Official Full Name: 2,4-dienoyl-CoA reductase 2provided by HGNC
Gene Summary: Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in cytosol and peroxisomal membrane. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28403 | DECR2 Knockout cell line (HeLa) | Human | DECR2 | 1:3~1:6 | Negative | Online Inquiry |
KO28404 | DECR2 Knockout cell line (HCT 116) | Human | DECR2 | 1:2~1:4 | Negative | Online Inquiry |
KO28405 | DECR2 Knockout cell line (HEK293) | Human | DECR2 | 1:3~1:6 | Negative | Online Inquiry |
KO28406 | DECR2 Knockout cell line (A549) | Human | DECR2 | 1:3~1:4 | Negative | Online Inquiry |
DECR2 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the function of the DECR2 gene, which encodes for the enzyme 2,4-dienoyl-CoA reductase 2. This enzyme plays a pivotal role in the fatty acid β-oxidation pathway, particularly in the metabolism of unsaturated fatty acids. These knockout cell lines serve as a valuable research tool, allowing scientists to elucidate the molecular mechanisms by which DECR2 influences lipid metabolism, energy homeostasis, and cellular signaling pathways.
The key function of DECR2 Gene Knockout Cell Lines is to enable researchers to observe the phenotypic and functional consequences of DECR2 gene deletion. By comparing knockout cells with wild-type counterparts, scientists can investigate alterations in metabolic profiles, mitochondrial function, and cellular responses to stress. This mechanistic understanding is critical for advances in metabolic health research and can illuminate potential therapeutic targets for lipid metabolism-related disorders.
The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. They are instrumental in drug development, enabling researchers to assess the efficacy of compounds aimed at modulating fatty acid metabolism. Additionally, these cell lines facilitate the study of diseases linked to dysregulated lipid metabolism, such as obesity, type 2 diabetes, and certain cardiovascular diseases.
Unique selling points of DECR2 Gene Knockout Cell Lines include their high specificity for the DECR2 gene, validated knockout efficiency, and ease of use. Unlike alternative models that may present variable results, these cell lines provide consistent and reliable data, significantly enhancing experimental reproducibility.
For researchers and clinicians focused on metabolic disorders, the value of DECR2 Gene Knockout Cell Lines lies in their capacity to advance our understanding of complex biochemical pathways and support the development of innovative therapeutic strategies. With a commitment to providing precision tools for genetic research, our company leverages cutting-edge gene editing technology and extensive expertise in cellular models to deliver reliable products tailored to the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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