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DCUN1D4 Knockout Cell Lines

Gene: DCUN1D4

Official Full Name: defective in cullin neddylation 1 domain containing 4provided by HGNC

Gene Summary: Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29808 DCUN1D4 Knockout cell line (HeLa) Human DCUN1D4 1:3~1:6 Negative Online Inquiry
KO29809 DCUN1D4 Knockout cell line (HCT 116) Human DCUN1D4 1:2~1:4 Negative Online Inquiry
KO29810 DCUN1D4 Knockout cell line (HEK293) Human DCUN1D4 1:3~1:6 Negative Online Inquiry
KO29811 DCUN1D4 Knockout cell line (A549) Human DCUN1D4 1:3~1:4 Negative Online Inquiry

Background

DCUN1D4 Gene Knockout Cell Lines represent a pioneering approach in genetic research and therapeutic development, focusing on the specific ablation of the DCUN1D4 gene, which is crucial for regulating the ubiquitin-proteasome system. This innovative product allows researchers to study the functional consequences of DCUN1D4 loss at both cellular and molecular levels, thereby elucidating its role in various biological processes such as cell proliferation, differentiation, and response to stress. By employing CRISPR-Cas9 technology, this product creates defined, stable knockout models that facilitate the investigation of gene function without the confounding presence of wild-type alleles.

The primary mechanism of the DCUN1D4 knockout cell lines involves targeted genomic modifications that create frameshift mutations, effectively silencing the gene. This allows for detailed studies on the downstream effects of DCUN1D4 loss, potentially influencing pathways related to oncogenesis and disease progression. Its relevance extends to both fundamental biological research and clinical implications, making it a powerful tool for discovering novel therapeutic targets and strategies in diseases linked to ubiquitin-related pathways.

In comparison to traditional knockout methodologies, the DCUN1D4 Gene Knockout Cell Lines offer enhanced specificity, efficiency, and reproducibility, minimizing off-target effects and maximizing experimental reliability. Researchers can gain insights into the gene's role in various disease contexts, thus accelerating the translation of findings into clinical applications.

The introduction of these knockout cell lines offers significant advantages to researchers and clinicians alike, including the ability to streamline experimental designs, reduce timelines in functional studies, and ultimately advance the understanding of gene function in a variety of disease states. Our company prides itself on its extensive expertise in genetic engineering and cell line development, ensuring that this product line adheres to the highest standards of quality and innovation. By providing researchers with the tools to dissect complex genetic interactions, we contribute to the broader landscape of genetic research and therapeutic interventions.

Please note that all services are for research use only. Not intended for any clinical use.

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