Gene: DBP
Official Full Name: D-box binding PAR bZIP transcription factorprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04994 | DBP Knockout cell line (HeLa) | Human | DBP | 1:3~1:6 | Negative | Online Inquiry |
KO04995 | DBP Knockout cell line (HCT 116) | Human | DBP | 1:2~1:4 | Negative | Online Inquiry |
KO04996 | DBP Knockout cell line (HEK293) | Human | DBP | 1:3~1:6 | Negative | Online Inquiry |
KO04997 | DBP Knockout cell line (A549) | Human | DBP | 1:3~1:4 | Negative | Online Inquiry |
DBP Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted gene editing to inactivate the DBP (D-binding protein) gene. This innovative tool provides researchers with a reliable experimental model for examining the physiological and molecular consequences of DBP absence, which is crucial for understanding its role in various biological processes, such as circadian regulation and metabolic pathways.
These knockout cell lines function by utilizing CRISPR/Cas9 technology, which allows for precise modifications at the genomic level. The deletion of the DBP gene results in a cellular environment that mimics specific disease states, enabling researchers to study the gene's function in greater depth. This mechanism not only facilitates the analysis of gene function and activity but also contributes to the exploration of potential therapeutic targets and biomarkers in related conditions.
The scientific importance of DBP Gene Knockout Cell Lines extends into both research and clinical settings. They provide valuable insight for studies focused on sleep disorders, metabolic syndromes, and other related diseases where DBP is implicated. Understanding these functions can lead to novel therapeutic strategies, making these cell lines indispensable for translational research.
What sets DBP Gene Knockout Cell Lines apart from traditional cell models is their specificity and accuracy. By eliminating the confounding variables associated with wild-type cell lines, researchers can draw more reliable conclusions about the role of the DBP gene in cellular physiology. Moreover, these cell lines are easily scalable and compatible with high-throughput applications, streamlining the experimental process.
For researchers, clinicians, and drug developers, the DBP Gene Knockout Cell Lines represent a valuable asset in the toolbox for investigating gene function and developing targeted therapies. Available through our company, which specializes in advanced genetic modifications and cell line development, these products embody our commitment to enhancing research capabilities and accelerating scientific discovery in the field of cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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