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CYB5B Knockout Cell Lines

Gene: CYB5B

Official Full Name: cytochrome b5 type Bprovided by HGNC

Gene Summary: Enables heme binding activity. Contributes to nitrite reductase (NO-forming) activity. Involved in nitric oxide biosynthetic process. Located in membrane. Part of nitric-oxide synthase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25908 CYB5B Knockout cell line (HeLa) Human CYB5B 1:3~1:6 Negative Online Inquiry
KO25909 CYB5B Knockout cell line (HCT 116) Human CYB5B 1:2~1:4 Negative Online Inquiry
KO25910 CYB5B Knockout cell line (HEK293) Human CYB5B 1:3~1:6 Negative Online Inquiry
KO25911 CYB5B Knockout cell line (A549) Human CYB5B 1:3~1:4 Negative Online Inquiry

Background

CYB5B Gene Knockout Cell Lines are specialized cellular models designed to elucidate the roles and functions of the cytochrome b5 type B (CYB5B) gene in various biological pathways. These genetically modified cell lines have been engineered to lack functional CYB5B protein, allowing researchers to study the consequences of its absence on cellular metabolism, signal transduction, and redox biology. The knockout mechanism typically involves CRISPR-Cas9 technology or homologous recombination strategies, enabling precise genetic alterations that generate a reliable and reproducible model for experimentation.

The primary function of CYB5B is to participate in electron transport processes, impacting fatty acid desaturation and metabolism of various bioactive molecules. By utilizing these knockout cell lines, researchers can investigate alterations in lipid metabolic pathways, enzyme activity, and cellular response mechanisms triggered by oxidative stress. This is especially significant in the context of diseases such as diabetes, cardiovascular disorders, and cancer, where CYB5B has been implicated.

In terms of scientific significance, the CYB5B Gene Knockout Cell Lines are invaluable for both fundamental research and clinical applications, including drug discovery and toxicity assays. Unlike alternative cell lines that may exhibit variances in metabolic function and stress response, these knockout models provide a homogenous background to evaluate the specific contributions of the CYB5B gene, enhancing the reliability of experimental results.

For researchers and clinicians seeking to deepen their understanding of metabolic dysfunctions, these cell lines present a robust tool for targeted studies and therapeutic strategies. They allow for the exploration of biomolecular interactions and disease pathophysiology with greater precision.

With extensive experience in developing specialized biological products, our company excels in providing top-tier research tools, including CYB5B Gene Knockout Cell Lines. By ensuring high quality and reproducibility, we facilitate groundbreaking research that drives scientific discovery and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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