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CRACR2B Knockout Cell Lines

Gene: CRACR2B

Official Full Name: calcium release activated channel regulator 2Bprovided by HGNC

Gene Summary: Predicted to enable calcium ion binding activity. Involved in store-operated calcium entry. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18545 CRACR2B Knockout cell line (HeLa) Human CRACR2B 1:3~1:6 Negative Online Inquiry
KO18546 CRACR2B Knockout cell line (HCT 116) Human CRACR2B 1:2~1:4 Negative Online Inquiry
KO18547 CRACR2B Knockout cell line (HEK293) Human CRACR2B 1:3~1:6 Negative Online Inquiry
KO18548 CRACR2B Knockout cell line (A549) Human CRACR2B 1:3~1:4 Negative Online Inquiry

Background

CRACR2B Gene Knockout Cell Lines are engineered cellular models specifically designed to study the functional implications of the CRACR2B gene in various biological processes. These cell lines have been genetically modified using advanced CRISPR/Cas9 technology to create precise knockout mutations, effectively silencing the CRACR2B gene. This allows researchers to dissect the cellular roles of CRACR2B in fundamental processes such as calcium signaling, immune responses, and cellular motility, paving the way for insights into disorders where these pathways are disrupted.

The primary mechanism by which CRACR2B influences cellular behavior is through its involvement in the regulation of calcium release-activated calcium (CRAC) channels. By knocking out the CRACR2B gene, researchers can observe resultant changes in calcium influx and downstream signaling, facilitating a better understanding of calcium-mediated physiological responses. This is particularly relevant in cancer research, neurobiology, and immunology, where calcium signaling plays a critical role.

The scientific importance of CRACR2B Gene Knockout Cell Lines extends to both fundamental research and clinical settings. Their unique applications range from drug screening to the investigation of genetic pathways involved in disease progression and treatment resistance. By elucidating the roles of CRACR2B, researchers can identify novel therapeutic targets and potential biomarkers, ultimately improving patient outcomes.

Compared to other available models, our CRACR2B knockout cell lines offer heightened precision, reproducibility, and ease of use. They are meticulously validated for stability and functional integrity, ensuring that researchers can trust the data these models provide. Furthermore, the simplicity of utilizing these knockout cell lines allows for broader accessibility, making them suitable for both experienced scientists and those new to genetic research.

In conclusion, CRACR2B Gene Knockout Cell Lines represent a valuable resource for elucidating gene function and dysfunction, vital for advancing biological research and therapeutic strategies. As a leader in providing high-quality biological models, our company is committed to supporting scientific inquiry with tools designed to accelerate discovery and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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