Gene: CPLANE2
Official Full Name: ciliogenesis and planar polarity effector complex subunit 2provided by HGNC
Gene Summary: Predicted to enable GTP binding activity. Predicted to be involved in cilium assembly; protein localization; and regulation of vesicle-mediated transport. Predicted to act upstream of or within several processes, including axoneme assembly; endocardial cushion fusion; and regulation of smoothened signaling pathway. Located in centriole; ciliary basal body; and ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18564 | CPLANE2 Knockout cell line (HeLa) | Human | CPLANE2 | 1:3~1:6 | Negative | Online Inquiry |
KO18565 | CPLANE2 Knockout cell line (HCT 116) | Human | CPLANE2 | 1:2~1:4 | Negative | Online Inquiry |
KO18566 | CPLANE2 Knockout cell line (HEK293) | Human | CPLANE2 | 1:3~1:6 | Negative | Online Inquiry |
KO18567 | CPLANE2 Knockout cell line (A549) | Human | CPLANE2 | 1:3~1:4 | Negative | Online Inquiry |
CPLANE2 Gene Knockout Cell Lines represent a groundbreaking advancement in genetic research, specifically designed to facilitate the study of the CPLANE2 gene’s role in cellular processes. These cell lines have been engineered to create precise deletions in the CPLANE2 gene, enabling researchers to investigate the gene's functions in-depth and examine its contributions to various biological pathways and disease mechanisms.
The key function of CPLANE2 Gene Knockout Cell Lines is to provide a reliable model for studying gene expression and regulation, as well as the resulting phenotypic consequences of the gene deletion. Through CRISPR-Cas9 technology or homologous recombination techniques, these cell lines ensure accurate and efficient gene editing, allowing researchers to elucidate the molecular underpinnings of diseases that are thought to be linked to CPLANE2 dysregulation, such as ciliopathies and other developmental disorders.
In research and clinical settings, these knockout cell lines hold significant scientific importance. They serve as a vital tool for drug development, toxicological assessments, and the exploration of gene therapy approaches. By understanding how the loss of CPLANE2 function impacts cellular behavior, researchers can better target therapeutic strategies aimed at restoring normal function in affected tissues.
One of the primary advantages of the CPLANE2 Gene Knockout Cell Lines compared to alternative models is their specificity and accuracy. Unlike traditional cell lines, which may not completely replicate the effects of gene deletion due to background activity from other genes, these knockout lines provide a clean genetic slate, ensuring that observed results are directly attributable to the absence of CPLANE2. This specificity improves the reliability of research outcomes and accelerates the discovery process.
For researchers, clinicians, and pharmaceutical developers, the value of the CPLANE2 Gene Knockout Cell Lines is immense. They enable the exploration of critical questions in genetics and cell biology, ultimately contributing to significant advancements in therapeutic interventions. The ability to manipulate cellular mechanisms with precision supports innovative research and fosters the development of cutting-edge treatments.
Our company has a long-standing expertise in producing high-quality, genetically engineered cell lines tailored to meet the needs of the scientific community. With a commitment to innovation and excellence, our products are designed to empower researchers and enable them to achieve their scientific goals effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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