Gene: CNOT11
Official Full Name: CCR4-NOT transcription complex subunit 11provided by HGNC
Gene Summary: Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18636 | CNOT11 Knockout cell line (HeLa) | Human | CNOT11 | 1:3~1:6 | Negative | Online Inquiry |
KO18637 | CNOT11 Knockout cell line (HCT 116) | Human | CNOT11 | 1:2~1:4 | Negative | Online Inquiry |
KO18638 | CNOT11 Knockout cell line (HEK293) | Human | CNOT11 | 1:3~1:6 | Negative | Online Inquiry |
KO18639 | CNOT11 Knockout cell line (A549) | Human | CNOT11 | 1:3~1:4 | Negative | Online Inquiry |
CNOT11 Gene Knockout Cell Lines are specially engineered cellular models that have been modified to completely eliminate the expression of the CNOT11 gene. This gene encodes a component of the CCR4-NOT complex, which plays a significant role in mRNA degradation and regulation. By knocking out CNOT11, researchers can investigate the gene's functional contributions to various biological processes, including gene expression regulation, mRNA stability, and cellular response to stress. These cell lines serve as powerful tools for elucidating the pathways and mechanisms associated with gene regulation.
The primary function of CNOT11 Gene Knockout Cell Lines is to facilitate in-depth studies of gene function and interaction networks. By utilizing CRISPR/Cas9 technology for precise gene editing, these cell lines provide clear insights into the physiological and pathological roles of CNOT11. Researchers can perform comparative analyses of gene expression, cellular assays, and functional studies that help illuminate the consequences of CNOT11 loss, making these cell lines invaluable for exploring the gene's potential links to diseases such as cancer and neurodegenerative disorders.
CNOT11 Gene Knockout Cell Lines have broad scientific importance, particularly in research settings focused on molecular biology, genetics, and therapeutics development. Their application extends to drug discovery, where understanding the role of CNOT11 can reveal novel therapeutic targets and biomarkers for disease diagnosis. Additionally, these cell lines can be used to validate gene targets identified in high-throughput screening assays, thereby enhancing the development of more effective treatment strategies.
One of the unique selling points of our CNOT11 Gene Knockout Cell Lines is the high efficiency and specificity of the gene editing process, which ensures consistent results across experiments. Compared to conventional methods, our engineered cell lines offer unparalleled reliability, saving researchers valuable time and resources. Moreover, they come with comprehensive characterizations, ensuring researchers have all necessary information to integrate these models into their studies seamlessly.
For researchers and clinicians seeking to advance their understanding of the role of specific genes, particularly in the context of complex biological systems, CNOT11 Gene Knockout Cell Lines provide a sophisticated platform for exploration and discovery. With our commitment to high-quality biological products and extensive expertise in cell line development, we ensure that our customers receive not only top-tier products but also comprehensive support for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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