Gene: CIT
Official Full Name: citron rho-interacting serine/threonine kinaseprovided by HGNC
Gene Summary: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02552 | CIT Knockout cell line (HeLa) | Human | CIT | 1:3~1:6 | Negative | Online Inquiry |
KO02553 | CIT Knockout cell line (HCT 116) | Human | CIT | 1:2~1:4 | Negative | Online Inquiry |
KO02554 | CIT Knockout cell line (HEK293) | Human | CIT | 1:3~1:6 | Negative | Online Inquiry |
KO02555 | CIT Knockout cell line (A549) | Human | CIT | 1:3~1:4 | Negative | Online Inquiry |
CIT Gene Knockout Cell Lines are genetically engineered cell lines that have been meticulously designed to facilitate the study of gene function, signaling pathways, and the role of specific genes in various biological processes. This product features precise gene knockouts achieved through advanced CRISPR/Cas9 technology, allowing researchers to create inactivation of targeted genes with high specificity and efficiency.
The primary function of CIT Gene Knockout Cell Lines is to provide a robust platform for functional genomics studies. By selectively disabling specific genes, researchers can evaluate the phenotypic consequences and assess the biological roles of these genes in cellular context. This enables in-depth investigation of cellular pathways, drug responses, and disease mechanisms, offering insights that are crucial for understanding complex biological systems.
Scientifically, these cell lines hold significant importance in both research and clinical settings. They serve as invaluable tools for drug discovery, oncology research, and the validation of therapeutic targets. With the growing demand for personalized medicine, CIT Gene Knockout Cell Lines are essential for developing models that accurately mimic human diseases, thus enhancing translational research and clinical applications.
Compared to traditional gene silencing techniques, such as RNA interference, CIT Gene Knockout Cell Lines provide permanent and stable gene knockouts, ensuring that results are reproducible and reflect true gene function without off-target effects. This unique feature reduces variability and improves experimental fidelity, making these cell lines a superior choice for rigorous scientific investigation.
For researchers and clinicians alike, the value of CIT Gene Knockout Cell Lines lies in their ability to streamline experimental design and enhance understanding of molecular biology. By utilizing these advanced cell models, users can accelerate innovation in their projects while driving forward discoveries that have profound implications in therapeutic development.
With a commitment to providing cutting-edge biological products, our company specializes in delivering high-quality genetic engineering solutions that empower the scientific community, enabling transformative research and fostering advancements in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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