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CHPT1 Knockout Cell Lines

Gene: CHPT1

Official Full Name: choline phosphotransferase 1provided by HGNC

Gene Summary: Enables diacylglycerol cholinephosphotransferase activity. Involved in phosphatidylcholine biosynthetic process and platelet activating factor biosynthetic process. Is active in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18712 CHPT1 Knockout cell line (HeLa) Human CHPT1 1:3~1:6 Negative Online Inquiry
KO18713 CHPT1 Knockout cell line (HCT 116) Human CHPT1 1:2~1:4 Negative Online Inquiry
KO18714 CHPT1 Knockout cell line (HEK293) Human CHPT1 1:3~1:6 Negative Online Inquiry
KO18715 CHPT1 Knockout cell line (A549) Human CHPT1 1:3~1:4 Negative Online Inquiry

Background

CHPT1 Gene Knockout Cell Lines are genetically engineered cell lines in which the CHPT1 gene has been specifically disrupted or removed. This gene plays a pivotal role in regulating phospholipid metabolism and is implicated in various cellular functions, including membrane integrity and signal transduction. The knockout of the CHPT1 gene allows researchers to study its influence on cellular pathways and metabolic processes, providing insight into conditions such as cancer, neurodegenerative diseases, and metabolic disorders.

The primary mechanism by which CHPT1 gene knockout exerts its effects involves the alteration of phospholipid profiles within the membrane, leading to changes in biomolecular interactions and cellular signaling cascades. By creating a loss-of-function scenario, researchers can analyze downstream effects and assess functional compensatory mechanisms that occur in its absence. This makes CHPT1 knockout cell lines an invaluable tool for dissecting the biological roles of this gene in both normal physiology and pathological conditions.

The scientific importance of these cell lines extends to various applications in research and clinical settings. They enable the exploration of gene function, drug targeting, and the elucidation of disease mechanisms, offering a platform for high-throughput screening of pharmaceutical compounds. Compared to conventional cell lines, CHPT1 knockout lines provide a more precise model for studying gene-specific effects, enhancing the relevancy and accuracy of experimental outcomes.

One significant advantage of using CHPT1 Gene Knockout Cell Lines is the ability to achieve targeted investigations with consistency and reproducibility, minimizing off-target effects that often accompany less precise genetic manipulation techniques. Furthermore, these cell lines come with comprehensive validation and characterization data, ensuring confidence in their utility as reliable experimental models.

For researchers and clinicians alike, the CHPT1 Gene Knockout Cell Lines represent a critical advancement in the pursuit of knowledge surrounding gene function and its implications in health and disease. By employing this innovative product, users can advance their studies and potentially contribute to the development of novel therapeutic strategies. Our company prides itself on its expertise in genetic engineering and cell line development, offering high-quality biological products designed to accelerate research and enhance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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