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CHIC1 Knockout Cell Lines

Gene: CHIC1

Official Full Name: cysteine rich hydrophobic domain 1provided by HGNC

Gene Summary: This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in mouse. Experiments with other CHIC domain-containing family members show that the cysteine residues are palmitoylated post-translationally, resulting in membrane association. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21966 CHIC1 Knockout cell line (HeLa) Human CHIC1 1:3~1:6 Negative Online Inquiry
KO21967 CHIC1 Knockout cell line (HEK293) Human CHIC1 1:3~1:6 Negative Online Inquiry
KO21968 CHIC1 Knockout cell line (A549) Human CHIC1 1:3~1:4 Negative Online Inquiry

Background

CHIC1 Gene Knockout Cell Lines are advanced biological tools designed for gene function studies and therapeutic research involving the CHIC1 (Casking Interacting Protein 1) gene. These cell lines are engineered through CRISPR-Cas9 gene editing technology, ensuring precise deletion of the CHIC1 gene, making them an invaluable resource for elucidating the biological role of CHIC1 in various cellular processes, including endosomal trafficking and cytokine signaling.

The primary function of these knockout cell lines is to serve as a model for investigating the consequences of CHIC1 loss on cell behavior, proliferation, and apoptosis. By examining the phenotypic and molecular alterations that arise in CHIC1-deficient cells, researchers can gain insights into the gene's specific contributions to cellular homeostasis and its implications in diseases such as cancer and neurodegenerative disorders. This product enables scientists to perform targeted experiments that can elucidate the pathways and mechanisms altered in the absence of CHIC1, further establishing its biological relevance.

The scientific importance of CHIC1 Gene Knockout Cell Lines lies in their applicability across a range of research scenarios, from basic biological studies to the development of therapeutic interventions. In the clinical setting, understanding the role of CHIC1 could potentially lead to innovative strategies for managing diseases associated with its dysfunction.

What sets these knockout cell lines apart from traditional models is their specificity, speed, and reliability. Unlike less targeted approaches, our CHIC1 knockout cell lines provide definitive insights into gene function without the confounding variables of off-target effects. Additionally, they are readily compatible with various assay formats, facilitating easy integration into established workflows.

The value of CHIC1 Gene Knockout Cell Lines to researchers and clinicians is profound; they represent a cutting-edge means of advancing our knowledge of gene function and its implications in health and disease. By choosing this product, research laboratories can ensure they are utilizing the most modern techniques to uncover novel biological mechanisms and therapeutic targets.

As a leader in the field of genetic engineering, our company brings extensive expertise to the development of precision biological products, ensuring that our CHIC1 Gene Knockout Cell Lines meet the highest standards of scientific rigor and utility, fostering advancements in research and clinical applications alike.

Please note that all services are for research use only. Not intended for any clinical use.

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