Gene: CEP89
Official Full Name: centrosomal protein 89provided by HGNC
Gene Summary: Involved in non-motile cilium assembly. Acts upstream of or within cilium assembly. Located in several cellular components, including microtubule cytoskeleton; mitochondrial intermembrane space; and non-motile cilium. Part of ciliary transition fiber. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24518 | CEP89 Knockout cell line (HeLa) | Human | CEP89 | 1:3~1:6 | Negative | Online Inquiry |
KO24519 | CEP89 Knockout cell line (HCT 116) | Human | CEP89 | 1:2~1:4 | Negative | Online Inquiry |
KO24520 | CEP89 Knockout cell line (HEK293) | Human | CEP89 | 1:3~1:6 | Negative | Online Inquiry |
KO24521 | CEP89 Knockout cell line (A549) | Human | CEP89 | 1:3~1:4 | Negative | Online Inquiry |
CEP89 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CEP89 gene, which plays a critical role in centrosome function and cell cycle regulation. These cell lines facilitate investigations into the biological pathways influenced by CEP89, providing researchers with powerful tools to elucidate its implications in cellular stability, proliferation, and tumorigenesis.
The primary function of the CEP89 knockout cell lines is to allow scientists to study the effects of the absence of this gene on cellular processes. By observing changes in centrosome organization, mitotic spindle formation, and overall cell cycle dynamics, researchers can gain insights into the fundamental roles of CEP89 in maintaining cellular homeostasis and its potential contributions to diseases such as cancer.
The scientific importance of CEP89 knockout cell lines extends into various research and clinical settings. In basic research, they are pivotal for modeling diseases associated with centrosomal dysfunction, offering a platform for drug discovery and the development of therapeutic strategies. In clinical contexts, understanding CEP89 could lead to novel biomarkers for cancer prognosis or treatment response, emphasizing the relevance of these cell lines in translational science.
Compared to alternative models, CEP89 knockout cell lines provide a unique avenue to bypass compensatory mechanisms that might mask the gene's role, thus enabling clearer interpretations of experimental results. These cell lines are also characterized by their ease of use in various assays, including proliferation, migration, and invasion studies, making them adaptable for a wide range of experimental designs.
For researchers and clinicians alike, the availability of CEP89 Gene Knockout Cell Lines represents a valuable resource for advancing our understanding of centrosome biology and its implications in health and disease. By utilizing this product, you are equipped with cutting-edge tools reflecting the latest advancements in genetic engineering.
Our company prides itself on delivering high-quality biological products, facilitated by years of expertise in cell line development and genetic engineering. We are dedicated to supporting the scientific community with innovative solutions that empower research advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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