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CEND1 Knockout Cell Lines

Gene: CEND1

Official Full Name: cell cycle exit and neuronal differentiation 1provided by HGNC

Gene Summary: The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22722 CEND1 Knockout cell line (A549) Human CEND1 1:3~1:4 Negative Online Inquiry

Background

CEND1 Gene Knockout Cell Lines are sophisticated biological tools specifically designed to facilitate the study of the CEND1 gene, which plays a critical role in cancer progression and cellular signaling pathways. These engineered cell lines have undergone targeted gene editing, employing CRISPR-Cas9 or similar genome-editing technologies, to effectively ablate the expression of CEND1. This knockout mechanism allows researchers to elucidate the gene’s functions in various cellular contexts, such as proliferation, migration, and response to therapeutic agents.

The key function of CEND1 Gene Knockout Cell Lines lies in their ability to serve as models for investigating the biological ramifications of CEND1 depletion. This is particularly essential for understanding its contributions to cancer pathophysiology, where it may influence tumor growth and metastasis. Researchers can conduct high-throughput screening and functional assays using these cell lines to identify novel therapeutic targets or evaluate the efficacy of existing therapies in a more precise manner.

From a scientific perspective, the importance of CEND1 Gene Knockout Cell Lines extends to their applications in both fundamental and applied research. In preclinical studies, the insights gained from these models can lead to the development of targeted cancer therapies, providing significant clinical relevance. Their versatility also allows for use in drug discovery, gene function studies, and even regenerative medicine.

Compared to conventional cell lines that express the CEND1 gene, our knockout models provide a unique advantage by eliminating background signals that could confound experimental results. The specificity and precision of CEND1 gene knockout significantly enhance the reliability of data obtained from downstream applications. Researchers can trust that the phenotypes and therapeutic responses observed are truly attributable to the loss of CEND1 function.

For researchers, clinicians, and biopharmaceutical companies focused on cancer research and treatment development, CEND1 Gene Knockout Cell Lines represent a valuable resource. They offer robust support for cutting-edge scientific inquiry and pave the way for breakthroughs in understanding cancer biology. Our company's commitment to producing high-quality, genetically modified cell lines exemplifies our expertise in cellular biology and our dedication to advancing research in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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