Gene: CDCP1
Official Full Name: CUB domain containing protein 1provided by HGNC
Gene Summary: This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20266 | CDCP1 Knockout cell line (HeLa) | Human | CDCP1 | 1:3~1:6 | Negative | Online Inquiry |
KO20267 | CDCP1 Knockout cell line (HCT 116) | Human | CDCP1 | 1:2~1:4 | Negative | Online Inquiry |
KO20268 | CDCP1 Knockout cell line (A549) | Human | CDCP1 | 1:3~1:4 | Negative | Online Inquiry |
CDCP1 Gene Knockout Cell Lines are engineered cellular models that lack the expression of the CDCP1 (CUB domain-containing protein 1) gene. This product provides researchers with a powerful tool to investigate the biological roles of CDCP1 in various cellular processes, including cell adhesion, migration, and signaling pathways implicated in tumorigenesis. By utilizing CRISPR-Cas9 technology or similar gene-editing techniques, these knockout cell lines enable the study of CDCP1's contribution to cancer biology and other related diseases through loss-of-function analyses.
The key mechanism inherent in these knockout cell lines is the complete absence of the CDCP1 protein, allowing for the dissection of its function in cellular environments. This is particularly crucial in understanding processes such as epithelial-to-mesenchymal transition (EMT), which plays a significant role in cancer metastasis. Researchers can utilize these cell lines to elucidate the downstream effects of CDCP1 depletion on tumor progression and response to therapies, facilitating the development of targeted treatment strategies.
From a scientific perspective, the importance of CDCP1 gene knockout cell lines lies in their potential applications in cancer research, drug development, and understanding cell biology. Researchers can employ these models to test the efficacy of novel therapeutics, explore mechanisms of resistance, and assess the impact of CDCP1 in various tissue types and experimental conditions.
Compared to alternative models, such as overexpression systems or non-specific knockdown approaches, our CDCP1 gene knockout cell lines provide unparalleled specificity and validate the direct role of CDCP1 in influencing cellular behavior. This specificity enhances experimental rigor and reliability in translating findings to clinical relevance.
Ultimately, these innovative cell lines are indispensable resources for researchers and clinicians aiming to uncover the complexities of tumor biology and develop pioneering therapeutic interventions. Our company prides itself on its commitment to providing high-quality biological products backed by rigorous scientific research and expertise. By choosing CDCP1 Gene Knockout Cell Lines, you are investing in a valuable asset that empowers discovery and innovation in the field of biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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