Gene: CCAR2
Official Full Name: cell cycle and apoptosis regulator 2provided by HGNC
Gene Summary: Enables RNA polymerase II complex binding activity and enzyme inhibitor activity. Involved in several processes, including mitochondrial fragmentation involved in apoptotic process; regulation of primary metabolic process; and regulation of signal transduction. Located in several cellular components, including mitochondrial matrix; nucleoplasm; and spindle. Part of DBIRD complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20771 | CCAR2 Knockout cell line (HeLa) | Human | CCAR2 | 1:3~1:6 | Negative | Online Inquiry |
KO20772 | CCAR2 Knockout cell line (HCT 116) | Human | CCAR2 | 1:2~1:4 | Negative | Online Inquiry |
KO20773 | CCAR2 Knockout cell line (HEK293) | Human | CCAR2 | 1:3~1:6 | Negative | Online Inquiry |
KO20774 | CCAR2 Knockout cell line (A549) | Human | CCAR2 | 1:3~1:4 | Negative | Online Inquiry |
CCAR2 Gene Knockout Cell Lines represent a pioneering biological tool designed for researchers engaged in gene function studies and therapeutic development. These cell lines are engineered to have a specific knockout of the CCAR2 gene, which encodes a critical regulatory protein involved in various cellular processes, including proliferation, differentiation, and apoptosis. By creating a complete loss-of-function model, these cell lines facilitate the investigation of CCAR2’s biological roles in health and disease.
The CCAR2 gene knockout is achieved through advanced CRISPR-Cas9 technology, ensuring a precise and efficient disruption of the target gene. This process allows scientists to explore the molecular pathways affected by CCAR2 deficiency, paving the way for enhanced understanding of its contributions to complex diseases, including cancer and metabolic disorders. Research utilizing these cell lines can reveal potential therapeutic targets and inform the development of novel treatment strategies.
One of the unique advantages of utilizing CCAR2 Gene Knockout Cell Lines is their versatility in various experimental settings, including drug screening, functional assays, and mechanistic studies. Compared to traditional methods such as siRNA or shRNA knockdown, the knockout approach provides a more stable and permanent alteration, ensuring reproducibility and consistency across experiments. This stability is paramount for researchers seeking to validate findings in preclinical models or even in future clinical applications.
Clinicians and researchers can leverage the insights gained from CCAR2 knockout studies to contribute meaningfully to the body of knowledge around gene functions and their implications in disease. Our commitment to high-quality, rigorously validated biological products positions us as leaders in the field, ensuring that our customers can rely on the scientific accuracy and reliability of our tools for critical research advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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