Gene: CARD19
Official Full Name: caspase recruitment domain family member 19provided by HGNC
Gene Summary: Predicted to enable CARD domain binding activity. Predicted to be involved in negative regulation of canonical NF-kappaB signal transduction. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25006 | CARD19 Knockout cell line (HeLa) | Human | CARD19 | 1:3~1:6 | Negative | Online Inquiry |
KO25007 | CARD19 Knockout cell line (HCT 116) | Human | CARD19 | 1:2~1:4 | Negative | Online Inquiry |
KO25008 | CARD19 Knockout cell line (HEK293) | Human | CARD19 | 1:3~1:6 | Negative | Online Inquiry |
KO25009 | CARD19 Knockout cell line (A549) | Human | CARD19 | 1:3~1:4 | Negative | Online Inquiry |
CARD19 Gene Knockout Cell Lines are specially engineered cellular models that feature a targeted deletion of the CARD19 gene, an essential component involved in various signaling pathways pertinent to immunity and cellular adhesion. Through advanced CRISPR-Cas9 technology, these cell lines enable researchers to elucidate the functional role of CARD19 in cellular processes, particularly in immune response regulation and the pathogenesis of related diseases.
The primary function of CARD19 Gene Knockout Cell Lines is to serve as a robust tool for studying gene function and potential therapeutic targets. The knockout results in a loss of CARD19 protein expression, allowing for the exploration of downstream effects on signaling cascades and elucidation of gene interactions in complex cellular environments. Utilizing these cell lines, researchers can assess changes in cell behavior, including apoptosis, migration, and inflammatory responses, providing insights into the underlying mechanisms of various conditions, including autoimmune diseases and cancers.
In terms of scientific importance, these cell lines offer a unique platform for both basic and applied research. They facilitate high-throughput screening for drug discovery and the development of innovative therapies targeting immune dysregulation. Furthermore, CARD19 Gene Knockout Cell Lines are invaluable in preclinical studies, providing critical data about gene function in vivo through the examination of knockout effects in differentiation, proliferation, and therapeutic responses.
Compared to other genetic models, the specificity and precision of our CARD19 Gene Knockout Cell Lines stand out. They ensure reproducibility and reliability in experimental results, significantly reducing the risk of off-target effects associated with alternative gene-editing methods. Our product's optimized design guarantees user-friendly applications, requiring minimal adaptation for various experimental setups.
Researchers and clinicians will find great value in using CARD19 Gene Knockout Cell Lines to deepen their understanding of immune mechanisms and to identify novel therapeutic pathways. By advancing knowledge in this critical area of biology, these cell lines support the paradigm of precision medicine, empowering tailored therapeutic strategies for patients.
Our company prides itself on its expertise in the development of high-quality biological research tools, ensuring that our products meet the highest standards of scientific rigor. With a commitment to advancing research, we provide comprehensive support and innovative solutions to accelerate the discovery process for our users.
Please note that all services are for research use only. Not intended for any clinical use.
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