Gene: CAMTA2
Official Full Name: calmodulin binding transcription activator 2provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29839 | CAMTA2 Knockout cell line (HeLa) | Human | CAMTA2 | 1:3~1:6 | Negative | Online Inquiry |
KO29840 | CAMTA2 Knockout cell line (HCT 116) | Human | CAMTA2 | 1:2~1:4 | Negative | Online Inquiry |
KO29841 | CAMTA2 Knockout cell line (HEK293) | Human | CAMTA2 | 1:3~1:6 | Negative | Online Inquiry |
KO29842 | CAMTA2 Knockout cell line (A549) | Human | CAMTA2 | 1:3~1:4 | Negative | Online Inquiry |
CAMTA2 Gene Knockout Cell Lines are specifically engineered cellular models in which the CAMTA2 gene has been disrupted using cutting-edge CRISPR-Cas9 gene-editing technology. These cell lines serve as essential tools for probing the functional significance of the CAMTA2 gene, a transcription factor implicated in various biological processes, including stress response and developmental regulation. The knockout of CAMTA2 allows researchers to study its downstream effects, providing insights into the gene’s role in cellular pathways.
The primary mechanism through which CAMTA2 gene knockout operates is the introduction of targeted mutations that effectively render the gene inactive. This alteration leads to the absence of CAMTA2 protein expression, enabling researchers to observe changes in gene expression profiles and cellular behavior, thereby elucidating the gene's contributions to pathophysiological conditions. Models lacking CAMTA2 can facilitate investigations into cancer biology, neurodegenerative diseases, and other disorders where CAMTA2 dysregulation is implicated.
The scientific importance of these cell lines resides in their ability to bridge the gap between genetic research and potential therapeutic advancements. They are invaluable in both preclinical research and drug development settings, allowing scientists to validate targets for therapeutic intervention or study the effects of pharmacological agents in a controlled environment.
Compared to traditional cell line models, CAMTA2 Gene Knockout Cell Lines offer distinct advantages, including precise genetic modifications and the capability to generate isogenic controls. These features enable higher reproducibility and more reliable data, setting a new standard for experimental rigor.
For researchers and clinicians aiming to unlock the mysteries of gene function and its implications in health and disease, CAMTA2 Gene Knockout Cell Lines represent a powerful resource. The ability to manipulate specific genetic elements within a cell provides a pathway to novel insights and therapeutic strategies.
Our company specializes in delivering high-quality biological products, including meticulously characterized knockout cell lines. With years of expertise in molecular biology and genetic engineering, we are committed to advancing research and development in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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