Gene: CAMSAP1
Official Full Name: calmodulin regulated spectrin associated protein 1provided by HGNC
Gene Summary: Enables microtubule minus-end binding activity and spectrin binding activity. Involved in several processes, including neuron projection development; regulation of cell morphogenesis; and regulation of microtubule polymerization. Located in microtubule minus-end. Implicated in complex cortical dysplasia with other brain malformations. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19105 | CAMSAP1 Knockout cell line (HeLa) | Human | CAMSAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO19106 | CAMSAP1 Knockout cell line (HCT 116) | Human | CAMSAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO19107 | CAMSAP1 Knockout cell line (HEK293) | Human | CAMSAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO19108 | CAMSAP1 Knockout cell line (A549) | Human | CAMSAP1 | 1:3~1:4 | Negative | Online Inquiry |
CAMSAP1 Gene Knockout Cell Lines are genetically engineered cell lines that have had the CAMSAP1 gene deactivated through precise gene editing techniques, such as CRISPR/Cas9. This product represents a powerful tool to study the role of CAMSAP1, a key protein involved in microtubule organization and cellular morphology. By creating these knockout cell lines, researchers can investigate the functional consequences of CAMSAP1 loss, elucidating pathways associated with cell division, polarity, and intracellular transport.
The primary mechanism of the CAMSAP1 knockout involves the disruption of microtubule polymerization, leading to altered cytoskeletal dynamics. CAMSAP1 is known to stabilize microtubules at the minus end and regulate their overall organization within the cell, contributing to effective cellular functions. By utilizing CAMSAP1 knockout cell lines, scientists can explore various biological processes, including cell migration, differentiation, and the implications of CAMSAP1 in diseases such as cancer, neurodegenerative disorders, and developmental anomalies.
The scientific importance of these cell lines extends to both research and clinical applications. They provide a valuable platform for drug discovery, allowing researchers to test novel therapeutic agents that target microtubule dynamics. Furthermore, understanding the role of CAMSAP1 in disease mechanisms can pave the way for the identification of biomarkers and therapeutic targets, enhancing our ability to develop precision medicine strategies.
Compared to other models, CAMSAP1 Gene Knockout Cell Lines offer unique advantages, including precise gene editing that ensures a complete loss of gene function, standardized protocols for easy manipulation, and reproducibility across experiments. This reliability is crucial for obtaining consistent and validated results, which are necessary for advancing scientific knowledge.
These knockout cell lines are invaluable resources for researchers and clinicians alike, as they enable the comprehensive study of CAMSAP1 in various biological contexts. By investing in this product, users gain access to cutting-edge technology that supports innovative research trajectories, ultimately contributing to advancements in the understanding of critical cellular processes.
Our company specializes in providing high-quality genetic models and bio-research tools, backed by extensive expertise in molecular biology. We are committed to supporting the scientific community with products that facilitate groundbreaking research and transformative clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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