Gene: CABP4
Official Full Name: calcium binding protein 4provided by HGNC
Gene Summary: This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19129 | CABP4 Knockout cell line (HeLa) | Human | CABP4 | 1:3~1:6 | Negative | Online Inquiry |
CABP4 Gene Knockout Cell Lines are genetically engineered cell cultures that enable the study and manipulation of the CABP4 gene, which encodes for the calcium-binding protein 4 involved in important physiological processes, particularly in the auditory system. By employing advanced CRISPR-Cas9 gene editing technology, these cell lines have had the CABP4 gene selectively targeted and disrupted, allowing researchers to elucidate its role in cellular signaling, calcium homeostasis, and neuronal function.
The primary mechanism through which the CABP4 gene knockout operates involves the precise alteration of the gene's coding sequence, effectively creating a loss-of-function model. This tool provides valuable insights into the molecular pathways modulated by CABP4, particularly its implications in auditory processing and potential links to hearing loss. Such a capability is crucial for researchers investigating the genetic and cellular bases of auditory disorders, enabling the development of targeted therapeutic strategies.
The scientific importance of CABP4 Gene Knockout Cell Lines extends beyond basic research; these models can be utilized in drug discovery, regenerative medicine, and therapeutics aimed at hearing impairments. Their versatility ensures they can be applied across various research contexts, from fundamental molecular biology to translational studies aimed at clinical application.
Compared to traditional knockout models, which may take considerable time and resources to develop, our cell lines offer immediate access to a ready-to-use platform. This significantly accelerates the research timeline and allows for cost-effective studies, thereby providing a strong competitive edge. Additionally, these cell lines have undergone rigorous validation for specificity and viability, ensuring that researchers are utilizing high-quality, reliable tools for their experiments.
For researchers, clinicians, and institutions focused on advancing auditory research or seeking novel therapeutic insights, CABP4 Gene Knockout Cell Lines represent a crucial asset that enhances experimental workflows and enriches data quality. Our commitment to innovative biological products stems from years of expertise in genetic engineering and cell line development, making our offerings not just tools, but essential components in the quest for scientific knowledge and medical advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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