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BEX4 Knockout Cell Lines

Gene: BEX4

Official Full Name: brain expressed X-linked 4provided by HGNC

Gene Summary: This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05505 BEX4 Knockout cell line (HCT 116) Human BEX4 1:2~1:4 Negative Online Inquiry
KO05506 BEX4 Knockout cell line (HEK293) Human BEX4 1:3~1:6 Negative Online Inquiry
KO05507 BEX4 Knockout cell line (A549) Human BEX4 1:3~1:4 Negative Online Inquiry

Background

BEX4 Gene Knockout Cell Lines are innovative cellular models engineered to facilitate the functional analysis of the BEX4 gene, which encodes a protein implicated in various biological processes, including cell proliferation and stress response. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines have been meticulously designed to create complete and stable BEX4 gene knockouts, allowing researchers to elucidate the gene's role in cellular pathways and its contribution to disease mechanisms.

The primary function of BEX4 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for investigating the effects of BEX4 loss on cellular behavior. Upon knockout, researchers can assess alterations in gene expression profiles, modulation of signaling cascades, and sensitivity to various stressors. This makes these cell lines invaluable for studying conditions such as cancer, neurodegenerative diseases, and metabolic disorders where BEX4 may have therapeutic implications.

In research and clinical settings, the BEX4 Gene Knockout Cell Lines serve as critical tools for drug discovery and development, enabling the screening of pharmacological agents and potential therapeutic compounds targeting pathways influenced by BEX4. Unique advantages of these cell lines include their robustness, reproducibility, and ease of use. Unlike traditional knockout models, these engineered cell lines allow for quicker experimental timelines and fewer resource-intensive breeding efforts, facilitating rapid results.

For researchers and clinicians, the BEX4 Gene Knockout Cell Lines represent a highly valuable asset in translational research, providing insights that can lead to innovative therapeutic strategies. With our company's extensive expertise in gene-editing technologies and cell line development, we are dedicated to providing cutting-edge products that support the advancement of molecular and cellular biology. Our commitment to quality and innovation ensures that you receive the most reliable tools for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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