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BEX1 Knockout Cell Lines

Gene: BEX1

Official Full Name: brain expressed X-linked 1provided by HGNC

Gene Summary: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in positive regulation of DNA-binding transcription factor activity and positive regulation of transcription by RNA polymerase II. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02030 BEX1 Knockout cell line (HEK293) Human BEX1 1:3~1:6 Negative Online Inquiry

Background

BEX1 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to entirely remove the BEX1 gene, a crucial gene implicated in various neurological processes and disorders. By utilizing advanced CRISPR/Cas9 technology, these cell lines facilitate the study of gene function and regulation in a controlled environment, providing researchers with a robust tool for investigating BEX1's role in cellular behaviors and signaling pathways.

The primary mechanism of action for these knockout cell lines involves the targeted disruption of the BEX1 gene, leading to a loss-of-function phenotype. This allows researchers to observe the cellular and molecular consequences of gene knockout, elucidating the pathways affected by BEX1 and permitting the examination of compensatory mechanisms that might arise. Such insights are invaluable in understanding the biological processes underpinning neurodevelopmental disorders and other related conditions.

The scientific importance of BEX1 Gene Knockout Cell Lines extends deeply into both basic and applied research. In clinical settings, such models are essential for drug discovery and development, enabling the identification of potential therapeutic targets associated with BEX1. Furthermore, they can be instrumental in the assessment of gene therapy approaches aimed at restoring function in patients with BEX1-related pathologies.

What sets these cell lines apart from alternative models is their high specificity and reliability in gene knockout, coupled with stringent quality control measures that ensure consistency across experiments. The ease of use in downstream applications, such as high-throughput screening, further enhances their appeal to researchers seeking efficient methodologies to validate hypotheses or engage in innovative research.

For researchers and clinicians, investing in BEX1 Gene Knockout Cell Lines represents an opportunity to explore the complexities of gene function and its implications in disease states. These models are not merely tools for experimentation; they are gateways to breakthrough discoveries that could inform future clinical practices and therapeutic interventions.

Our company is dedicated to advancing research in molecular biology by providing high-quality, precision-engineered biological products. Leveraging state-of-the-art technology and expertise, we ensure that our offerings, including the BEX1 Gene Knockout Cell Lines, empower the scientific community to drive meaningful progress in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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