Gene: BAIAP3
Official Full Name: BAI1 associated protein 3provided by HGNC
Gene Summary: This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33708 | BAIAP3 Knockout cell line (HCT 116) | Human | BAIAP3 | 1:2~1:4 | Negative | Online Inquiry |
KO33709 | BAIAP3 Knockout cell line (HEK293) | Human | BAIAP3 | 1:3~1:6 | Negative | Online Inquiry |
BAIAP3 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed for the functional study of the BAIAP3 gene, which encodes a protein involved in various cellular processes, including cytoskeletal dynamics and signal transduction. By knocking out the BAIAP3 gene, researchers can investigate the role of this protein in cellular functions and its implications in disease states.
These knockout cell lines function through the use of precise genome editing techniques, such as CRISPR/Cas9, to create targeted deletions in the BAIAP3 gene. This results in cells that lack the expression of BAIAP3, allowing for comparative studies against wild-type cells. The mechanism of action enables researchers to assess changes in cellular behavior, including proliferation, migration, and response to external stimuli, thereby elucidating the gene's biological significance.
The scientific importance of BAIAP3 knockout cell lines resides in their utility for basic and applied research, particularly in the realms of cancer biology, neurobiology, and cellular signaling. Understanding the role of BAIAP3 can uncover potential therapeutic targets and contribute to the development of novel treatment strategies. In clinical settings, these cell lines can serve as models for drug screening and toxicology assessments.
Compared to alternative products, BAIAP3 Gene Knockout Cell Lines provide a highly specific tool that eliminates the confounding effects of BAIAP3, allowing for clearer interpretation of experimental results. They are rigorously validated for consistent performance and reliability, making them a valuable addition to any laboratory focused on gene function analysis.
Researchers and clinicians seeking to deepen their understanding of gene regulation and its implications in health and disease will find these knockout cell lines indispensable. Their unique ability to aid in hypothesis-driven studies and drug development highlights their importance in advancing scientific knowledge.
Our company specializes in providing high-quality genetic engineering solutions, and our expertise in creating validated knockout models ensures that researchers receive top-tier support to facilitate their scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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