Gene: ASCC3
Official Full Name: activating signal cointegrator 1 complex subunit 3provided by HGNC
Gene Summary: This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00319 | ASCC3 Knockout cell line (HeLa) | Human | ASCC3 | 1:3~1:6 | Negative | Online Inquiry |
ASCC3 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the comprehensive study of the ASCC3 gene, which is known for its role in regulating cellular stress responses and promoting DNA damage repair mechanisms. These engineered cell lines are generated using sophisticated CRISPR-Cas9 gene editing technology, effectively leading to the complete ablation of the ASCC3 gene expression. This knockout allows researchers to investigate the downstream effects of ASCC3 loss on various cellular pathways, including those involved in apoptosis, autophagy, and genomic stability.
The mechanistic insights derived from ASCC3 Gene Knockout Cell Lines are invaluable for understanding the biological roles of ASCC3 in health and disease. In both research and clinical settings, this tool serves as an essential resource for dissecting the underlying pathways associated with cancer progression, neurodegenerative disorders, and other diseases characterized by impaired DNA repair mechanisms. Moreover, these cell lines can be utilized for drug screening, enabling researchers to explore novel therapeutic strategies targeting ASCC3-related pathways.
One of the significant advantages of ASCC3 Gene Knockout Cell Lines is their precision and reproducibility, which provides a reliable alternative to traditional gene knockdown methods that may yield inconsistent results. Furthermore, these knockout cell lines are carefully validated for consistent performance across different experimental conditions, ensuring high confidence in data interpretation.
For researchers and clinicians, the value of ASCC3 Gene Knockout Cell Lines lies in their potential to deepen our understanding of gene function and its implications in pathophysiology, ultimately aiding in the development of more targeted therapies. Our company, recognized for its commitment to advancing genetic and cellular research tools, offers ASCC3 Gene Knockout Cell Lines as part of a comprehensive product portfolio designed to empower researchers in their quest for scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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