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ARK2C Knockout Cell Lines

Gene: ARK2C

Official Full Name: arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2Cprovided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in motor neuron axon guidance and positive regulation of BMP signaling pathway. Predicted to act upstream of or within several processes, including forelimb morphogenesis; nervous system development; and protein polyubiquitination. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19691 ARK2C Knockout cell line (HeLa) Human ARK2C 1:3~1:6 Negative Online Inquiry
KO19692 ARK2C Knockout cell line (HCT 116) Human ARK2C 1:2~1:4 Negative Online Inquiry
KO19693 ARK2C Knockout cell line (HEK293) Human ARK2C 1:3~1:6 Negative Online Inquiry

Background

ARK2C Gene Knockout Cell Lines are specialized cellular models engineered to lack the ARK2C gene, which encodes a protein involved in critical cellular pathways. This innovative product serves as an essential tool for researchers exploring gene function, cellular signaling, and disease mechanisms. By providing a means to study the effects of complete ARK2C ablation, these cell lines facilitate the investigation of its role in various physiological and pathological contexts, including cancer progression and neurodegenerative disorders.

The key functions of ARK2C Gene Knockout Cell Lines center around their ability to mimic biological processes devoid of the ARK2C protein's influence. Researchers can employ these models to elucidate downstream effects on signal transduction pathways and determine how the absence of this gene affects cellular behavior, proliferation, and apoptosis. Additionally, these cell lines can be utilized in high-throughput screening assays to identify novel therapeutic compounds that target related pathways, thus accelerating drug discovery efforts.

The scientific importance of ARK2C Gene Knockout Cell Lines lies in their multifaceted applications across both basic research and clinical settings. In the lab, they enable investigators to delineate the gene’s functional contributions, while in a clinical context, they offer insights into potential biomarker development and therapeutic targets for various diseases. Compared to traditional models, ARK2C knockout lines provide a unique advantage by offering clean genetic backgrounds free from ARK2C activity, thus minimizing confounding factors.

The value of ARK2C Gene Knockout Cell Lines to researchers and clinicians is of paramount significance. By utilizing these lines, users can obtain comprehensive data that enhances the understanding of gene function and interaction networks, enabling advancements in precision medicine. Their robust performance and reliability make them a preferred choice for experimental validation and hypothesis testing.

Our company prides itself on a strong commitment to innovation and quality in biological products. With extensive expertise in genetic engineering, we provide researchers with cutting-edge tools that empower discoveries and drive progress in various fields of life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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