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ARHGAP32 Knockout Cell Lines

Gene: ARHGAP32

Official Full Name: Rho GTPase activating protein 32provided by HGNC

Gene Summary: RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32836 ARHGAP32 Knockout cell line (HeLa) Human ARHGAP32 1:3~1:6 Negative Online Inquiry
KO32837 ARHGAP32 Knockout cell line (HCT 116) Human ARHGAP32 1:2~1:4 Negative Online Inquiry
KO32838 ARHGAP32 Knockout cell line (HEK293) Human ARHGAP32 1:3~1:6 Negative Online Inquiry
KO32839 ARHGAP32 Knockout cell line (A549) Human ARHGAP32 1:3~1:4 Negative Online Inquiry

Background

ARHGAP32 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the Rho GTPase-activating protein 32 (ARHGAP32) functionality and its pathophysiological implications. By employing CRISPR-Cas9 technology, these cell lines have been specifically modified to lack the ARHGAP32 gene, enabling researchers to elucidate the role of ARHGAP32 in cellular processes such as cytoskeletal dynamics, cell migration, and signal transduction.

The key functions of ARHGAP32 include its regulatory role in Rho family GTPase activity, which influences a variety of biological processes, including cell proliferation, differentiation, and apoptosis. By utilizing these knockout cell lines, scientists can investigate the downstream effects of ARHGAP32 deletion, providing insights into its functional mechanisms in both normal physiology and disease states. This makes the ARHGAP32 knockout models valuable tools in cellular and molecular biology research, particularly in cancer biology and developmental studies.

Scientific applications of ARHGAP32 knockout cell lines extend beyond basic research; they also hold significant importance in the development of targeted therapies and precision medicine. By evaluating how the absence of ARHGAP32 affects cancer cell behavior and response to therapeutic agents, researchers can identify novel biomarkers and therapeutic targets.

What sets our ARHGAP32 Gene Knockout Cell Lines apart from competing products is our stringent validation process and commitment to quality. Each cell line is thoroughly characterized for genetic integrity and functional efficacy, ensuring reliable outcomes for experimental reproducibility. Moreover, we offer comprehensive technical support that empowers users to navigate their research challenges effectively.

In summary, the ARHGAP32 Gene Knockout Cell Lines represent a crucial resource for researchers and clinicians aiming to deepen their understanding of cell signaling pathways and their implications in health and disease. Backed by our company’s expertise in molecular genetics and commitment to advancing scientific discovery, we are proud to provide this innovative solution to the global research community.

Please note that all services are for research use only. Not intended for any clinical use.

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