Gene: APBB1IP
Official Full Name: amyloid beta precursor protein binding family B member 1 interacting proteinprovided by HGNC
Gene Summary: Predicted to be involved in signal transduction. Predicted to act upstream of or within T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and positive regulation of cell adhesion. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08723 | APBB1IP Knockout cell line (A549) | Human | APBB1IP | 1:3~1:4 | Negative | Online Inquiry |
APBB1IP Gene Knockout Cell Lines are specialized cellular models in which the APBB1IP gene has been specifically disrupted, enabling researchers to investigate the role of this gene in various biological processes. APBB1IP, or APBB1-interacting protein, has been implicated in critical cellular pathways, including those involved in signal transduction and cytoskeletal organization. The knockout of this gene allows for the examination of its function and interactions within cellular networks, providing a powerful tool to dissect the mechanisms underlying health and disease.
The primary function of the APBB1IP Gene Knockout Cell Lines is to facilitate studies on gene function and protein interactions. By eliminating the expression of the APBB1IP gene, researchers can elucidate its contributions to cellular processes such as growth, differentiation, and apoptosis. The knockout model effectively mimics loss-of-function scenarios, enabling a clearer understanding of the pathological implications related to APBB1IP dysregulation.
From a scientific standpoint, these knockout cell lines are invaluable in research settings aiming to explore mechanisms of diseases such as cancer, neurodegeneration, and metabolic disorders. They provide an advantageous platform for drug discovery, genetic screening, and toxicological studies, allowing researchers to assess the viability of pharmacological agents under conditions that accurately reflect the absence of the APBB1IP protein.
Compared to alternative models, such as overexpression systems or wild-type cells, APBB1IP Gene Knockout Cell Lines offer unique insights into gene function by presenting a clean background devoid of confounding signals. This specificity greatly enhances the reliability of experimental results, allowing for a more straightforward interpretation of data related to gene function.
The value of APBB1IP Gene Knockout Cell Lines to researchers and clinicians lies in their ability to provide a robust and reproducible model for studying gene-related phenomena. These cell lines not only advance our understanding of gene roles in diseases but also hold promise for identifying novel therapeutic targets.
Our company, with its extensive experience in creating customized cellular models, is committed to providing high-quality biological products that empower scientific discovery and innovation. The APBB1IP Gene Knockout Cell Lines represent a significant addition to our offerings, reflecting our dedication to supporting the needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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