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AP1AR Knockout Cell Lines

Gene: AP1AR

Official Full Name: adaptor related protein complex 1 associated regulatory proteinprovided by HGNC

Gene Summary: Enables AP-1 adaptor complex binding activity and kinesin binding activity. Involved in negative regulation of receptor recycling and vesicle targeting, trans-Golgi to endosome. Acts upstream of or within negative regulation of substrate adhesion-dependent cell spreading. Located in Golgi apparatus and transport vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19781 AP1AR Knockout cell line (HeLa) Human AP1AR 1:3~1:6 Negative Online Inquiry
KO19782 AP1AR Knockout cell line (HCT 116) Human AP1AR 1:2~1:4 Negative Online Inquiry
KO19783 AP1AR Knockout cell line (HEK293) Human AP1AR 1:3~1:6 Negative Online Inquiry
KO19784 AP1AR Knockout cell line (A549) Human AP1AR 1:3~1:4 Negative Online Inquiry

Background

AP1AR Gene Knockout Cell Lines are specialized cellular models that have undergone precise genetic modification to disrupt the expression of the AP1AR gene, a key player in various cellular signaling pathways. This innovative product enables researchers to study the functional implications of AP1AR gene deletion in real-time, providing insights into cellular behaviors, processes, and responses to environmental stimuli.

The primary mechanism at play involves the use of CRISPR-Cas9 gene-editing technology, which ensures a targeted and efficient knockout of the AP1AR gene. By effectively eliminating this gene, researchers can observe changes in gene expression, protein interactions, and cellular dynamics that are vital for understanding pathologies related to cell signaling misregulation, such as cancer and inflammatory diseases.

The scientific importance of AP1AR Gene Knockout Cell Lines is underscored by their applications in fundamental and applied research. They serve as invaluable tools in investigating therapeutic targets, validating novel drugs, and elucidating the molecular pathways that underpin various diseases. In clinical settings, understanding the role of AP1AR can pave the way for novel interventions and could transform treatment strategies for associated disorders.

Compared to alternative cell lines, AP1AR Gene Knockout Cell Lines offer enhanced specificity and reliability, facilitating reproducible experimental results. They are developed under rigorously controlled conditions, ensuring consistent performance and easier interpretation of data. Researchers will find that these knockout cell lines save time and resources, significantly improving experimental agility.

The AP1AR Gene Knockout Cell Lines embody our commitment to advancing scientific research by providing meticulously engineered models that empower discovery. Our expertise in genetic engineering and cellular biology positions us as a leader in delivering high-quality products that meet the evolving needs of researchers and clinicians alike.

Please note that all services are for research use only. Not intended for any clinical use.

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