Gene: ANKRD61
Official Full Name: ankyrin repeat domain 61provided by HGNC
Gene Summary: Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19806 | ANKRD61 Knockout cell line (HeLa) | Human | ANKRD61 | 1:3~1:6 | Negative | Online Inquiry |
KO19807 | ANKRD61 Knockout cell line (HCT 116) | Human | ANKRD61 | 1:2~1:4 | Negative | Online Inquiry |
KO19808 | ANKRD61 Knockout cell line (A549) | Human | ANKRD61 | 1:3~1:4 | Negative | Online Inquiry |
ANKRD61 Gene Knockout Cell Lines are engineered cellular models characterized by the targeted disruption of the ANKRD61 gene, which encodes a protein involved in various cellular processes including the modulation of inflammation and stress responses. These cell lines serve as valuable tools for assessing the functional role of ANKRD61 in different biological contexts. By removing the ANKRD61 gene, researchers can observe the phenotypical and molecular consequences of its absence, elucidating its contribution to various pathways and diseases, particularly those related to immune response and cellular signaling.
The core mechanism of these knockout cell lines involves the use of CRISPR-Cas9 technology, enabling precise genome editing. This allows researchers to create cell lines with a complete loss of ANKRD61 expression, facilitating investigation into its biological functions. By examining the altered cellular behavior in these knockout models, scientists can gain insights into mechanisms of disease, drug responses, and potential therapeutic targets, making these lines particularly important in both fundamental and applied research.
The scientific significance of ANKRD61 Gene Knockout Cell Lines extends to various applications in research and clinical settings, including drug discovery, gene function studies, and the development of novel therapeutic strategies. Their utilization can lead to breakthroughs in understanding the pathogenicity of diseases where ANKRD61 is implicated, thus contributing to advancements in personalized medicine.
What sets these knockout cell lines apart from alternative models is their specificity and reliability. Unlike other genetic modification approaches that may yield partial or variable outcomes, the CRISPR-mediated knockout provides a complete, reproducible gene loss, ensuring consistency in experimental results. Additionally, these cell lines can be easily incorporated into existing protocols, providing researchers with a ready-to-use resource that accelerates their studies.
For researchers, clinicians, and biopharmaceutical companies, investing in ANKRD61 Gene Knockout Cell Lines means leveraging a powerful, precise tool for uncovering complex biological relationships and developing targeted interventions. Our company prides itself on our expertise in genetic engineering and commitment to providing high-quality biological products that empower scientific innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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