Gene: AMDHD1
Official Full Name: amidohydrolase domain containing 1provided by HGNC
Gene Summary: Predicted to enable imidazolonepropionase activity. Predicted to be involved in L-histidine catabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24128 | AMDHD1 Knockout cell line (HCT 116) | Human | AMDHD1 | 1:2~1:4 | Negative | Online Inquiry |
KO24129 | AMDHD1 Knockout cell line (HEK293) | Human | AMDHD1 | 1:3~1:6 | Negative | Online Inquiry |
KO24130 | AMDHD1 Knockout cell line (A549) | Human | AMDHD1 | 1:3~1:4 | Negative | Online Inquiry |
AMDHD1 Gene Knockout Cell Lines are specialized cellular models that have undergone a targeted genetic modification to disrupt the function of the AMDHD1 gene. This gene encodes for an enzyme involved in the metabolism of specific fatty acids and the overall regulation of metabolic pathways. By knocking out the AMDHD1 gene, these cell lines provide a unique tool to investigate the biological role of this gene in various cellular processes and disease states, particularly those related to metabolic dysfunctions.
The primary function of AMDHD1 Gene Knockout Cell Lines is to enable researchers to explore the phenotypic consequences of the absence of this gene. Without the influence of AMDHD1, researchers can assess alterations in metabolic pathways, lipid profiles, and related enzymatic activities. This insight is crucial in elucidating the gene's role in diseases such as obesity, diabetes, and disorders linked to lipid metabolism.
The scientific importance of these knockout cell lines lies in their potential applications for both basic research and clinical settings. They can facilitate drug discovery processes by helping identify new therapeutic targets or biomarkers associated with metabolic diseases. Moreover, their use in academic research can advance our understanding of gene function and regulation in health and disease.
What sets AMDHD1 Gene Knockout Cell Lines apart from alternative models is their specificity and precision. While traditional models may not effectively isolate the effects of a single gene, these knockout lines provide a focused approach, allowing researchers to minimize variability and enhance the reliability of their results. Additionally, our cell lines are developed under stringent quality control measures, ensuring high levels of reproducibility and functionality.
For researchers and clinicians, the value of AMDHD1 Gene Knockout Cell Lines extends beyond mere research utility; they represent an opportunity to tap into a wealth of genetic insights that can lead to innovative solutions in treating metabolic disorders. By utilizing these cell lines, practitioners can gain a deeper understanding of disease mechanisms, ultimately driving forward the frontiers of medical science.
Our commitment to advancing biological research is underscored by our expertise in developing high-quality genetic models. We are dedicated to supporting the scientific community with reliable and innovative products that are poised to enhance research outcomes and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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