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ADGRG2 Knockout Cell Lines

Gene: ADGRG2

Official Full Name: adhesion G protein-coupled receptor G2provided by HGNC

Gene Summary: This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32224 ADGRG2 Knockout cell line (HeLa) Human ADGRG2 1:3~1:6 Negative Online Inquiry
KO32225 ADGRG2 Knockout cell line (HEK293) Human ADGRG2 1:3~1:6 Negative Online Inquiry
KO32226 ADGRG2 Knockout cell line (A549) Human ADGRG2 1:3~1:4 Negative Online Inquiry

Background

ADGRG2 Gene Knockout Cell Lines are sophisticated biological tools derived from mammalian cells that have been genetically modified to lack the ADGRG2 gene, which encodes for the adhesion G protein-coupled receptor G2. These cell lines serve as invaluable resources for researchers seeking to unravel the functional roles of ADGRG2 in various physiological and pathological processes. The mechanism behind the knockout involves precise techniques such as CRISPR-Cas9 or homologous recombination, which enable targeted gene disruption, thus allowing for detailed studies of signal transduction pathways associated with ADGRG2, including its involvement in cellular adhesion, migration, and proliferation.

The scientific significance of ADGRG2 Gene Knockout Cell Lines cannot be overstated. As ADGRG2 has been implicated in numerous conditions, including cancer metastasis and cardiovascular diseases, these cell lines facilitate the exploration of its underlying mechanisms in both basic research and translational applications. Researchers can utilize these models for drug screening, biomarker discovery, and elucidation of disease mechanisms, ultimately contributing to the development of novel therapeutic strategies.

What sets our ADGRG2 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, ensuring that the observed phenotype directly correlates with the absence of the gene of interest. Additionally, our cell lines are validated for consistent growth characteristics and signaling pathway responses, which enhance their reliability for experimental use.

For researchers and clinicians aiming to deepen their understanding of ADGRG2-related pathologies, these knockout cell lines offer a remarkable platform. Their ability to provide clear insights into gene function and interaction networks makes them essential for advancing knowledge and fostering innovation in the biomedical field.

Our company prides itself on delivering high-quality biological products, backed by extensive research and development efforts. With a commitment to excellence in genomic technologies, we empower the scientific community to spearhead transformative discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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