Gene: ADGRF1
Official Full Name: adhesion G protein-coupled receptor F1provided by HGNC
Gene Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including energy reserve metabolic process; fat cell differentiation; and nervous system development. Predicted to act upstream of or within memory and positive regulation of CREB transcription factor activity. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19986 | ADGRF1 Knockout cell line (HCT 116) | Human | ADGRF1 | 1:2~1:4 | Negative | Online Inquiry |
ADGRF1 Gene Knockout Cell Lines are specialized cellular models designed to study the function of the ADGRF1 gene, which encodes for a member of the adhesin G protein-coupled receptor family. These cell lines have been meticulously engineered through CRISPR/Cas9 technology to lack the ADGRF1 gene, thus providing researchers with a valuable tool for dissecting its role in cellular processes such as adhesion, signaling, and gene expression regulation.
The core function of these knockout cell lines lies in their ability to mimic the effects of ADGRF1 deficiency, allowing for in-depth examination of the biological consequences of gene loss. Researchers can utilize these cell lines to investigate the pathways and mechanisms modulated by ADGRF1, offering insights into its involvement in physiological and pathological conditions. This is particularly important for understanding diseases that may be linked to ADGRF1 dysfunction, such as neurological disorders or cancer.
From a scientific perspective, ADGRF1 gene knockout cell lines present unique advantages over traditional methods of gene silencing, such as RNA interference. They provide stable and long-term gene disruption, enabling consistent experimental conditions and reducing variability. Moreover, these models facilitate the exploration of complex cellular interactions and responses, which are often masked in transient knockdown systems.
For researchers and clinicians, these cell lines are invaluable for drug discovery and the development of therapeutic strategies. By elucidating the specific pathways influenced by ADGRF1, scientists can identify potential pharmacological targets and biomarkers, thus accelerating the translation of basic research into clinical applications.
Our company's expertise in gene editing and cell line development ensures that our ADGRF1 Gene Knockout Cell Lines are of the highest quality and reliability. We are committed to advancing biological research by providing innovative tools that empower researchers to unlock the mysteries of gene function and contribute to breakthroughs in medical science.
Please note that all services are for research use only. Not intended for any clinical use.
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