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SPDEF Knockout cell line (NCM460)

Catalog Number: KOA72104

Price: Online Inquiry

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Specifications

Product Information
Product Name SPDEF Knockout cell line (NCM460)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adheren
Passage ratio 1:2~1:3
species Human
Gene SPDEF
Gene ID 25803
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line NCM460
Quality Control Genotype: SPDEF Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name SAM pointed domain containing ETS transcription factorprovided by HGNC
Also known as PDEF; bA375E1.3
Gene Description The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Expression Biased expression in prostate (RPKM 50.1), salivary gland (RPKM 10.8) and 5 other tissues See more

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