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P2RX1 Knockout cell line (TPC-1)

Catalog Number: KOA60729

Price: Online Inquiry

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Specifications

Product Information
Product Name P2RX1 Knockout cell line (TPC-1)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:5-1:8
species Human
Gene P2RX1
Gene ID 5023
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%DMEM+10%FBS
Parental Cell Line TPC-1
Quality Control Genotype: P2RX1 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name purinergic receptor P2X 1provided by HGNC
Also known as P2X1
Gene Description The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
Expression Broad expression in bone marrow (RPKM 20.3), urinary bladder (RPKM 20.1) and 15 other tissues See more

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