TDO2 Knockout cell line (BEAS-2B)

Catalog Number: KOA28844

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Specifications

Product Information
Product Name	TDO2 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	TDO2
Gene ID	6999
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: TDO2 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	tryptophan 2,3-dioxygenaseprovided by HGNC
Also known as	TO; TDO; TPH2; TRPO; HYPTRP
Gene Description	This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
Expression	Biased expression in liver (RPKM 202.8) and appendix (RPKM 14.2) See more

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