STIP1 Knockout cell line (NCM460)

Catalog Number: KOA72937

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Specifications

Product Information
Product Name	STIP1 Knockout cell line (NCM460)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adheren
Passage ratio	1:2~1:3
species	Human
Gene	STIP1
Gene ID	10963
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	NCM460
Quality Control	Genotype: STIP1 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	stress induced phosphoprotein 1provided by HGNC
Also known as	HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521
Gene Description	STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
Expression	Ubiquitous expression in testis (RPKM 66.9), adrenal (RPKM 34.3) and 25 other tissues See more

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