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STC1 Knockout cell line (TPC-1)

Catalog Number: KOA59762

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Specifications

Product Information
Product Name STC1 Knockout cell line (TPC-1)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:5-1:8
species Human
Gene STC1
Gene ID 6781
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%DMEM+10%FBS
Parental Cell Line TPC-1
Quality Control Genotype: STC1 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name stanniocalcin 1provided by HGNC
Also known as STC
Gene Description This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
Expression Broad expression in endometrium (RPKM 33.6), thyroid (RPKM 19.7) and 14 other tissues See more

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